Rachel Bonami
Department of Medicine, Division of Rheumatology & Immunology
Department of Pathology, Microbiology and Immunology
Vanderbilt Institute for Infection, Immunology, and Inflammation (VI4)
Vanderbilt Center for Immunobiology
Computational Immunology Program
Human Immunology Discovery Initiative
Vanderbilt Diabetes Research and Training Center (DRTC)
Our overarching goal is to identify mechanisms by which autoantigen-specific B lymphocytes breach immune tolerance barriers to drive autoimmune disease. We apply cutting-edge hybridoma and single-cell RNAseq/CITEseq/BCRseq technology to study this process in type 1 diabetes, myositis, and immune checkpoint inhibitor-induced autoimmunity.
Keywords: immunology , computational immunology , B cell , type 1 diabetes , autoimmune disease ,
Research Area: Cancer Immunology , Computational and Systems Biology , Diabetes, Obesity, Metabolism , Immunology