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BRETBiomedical Research Education and Training

Ruben Martinez Barricarte

Department of Medicine, Division of Genetic Medicine
Department of Pathology, Microbiology and Immunology
Vanderbilt Genetics Institute (VGI)
Vanderbilt Center for Immunobiology
Vanderbilt Institute for Infection Immunology and Inflammation (VI4)

Inborn Errors of Immunity (IEI) are diseases characterized by impaired immune development or function, leading to severe infection, autoimmunity, and cancer. Our lab uses a combination of human genetics, human immunology, bioinformatics, and molecular biology to identify and functionally characterize disease-causing mutations in these patients. This work paves the way to provide genetic diagnosis and personalized treatment for patients and allows us to identify new mechanisms of human immunity.

Keywords: Human genetics , Immunology , Infectious diseases , Primary Immunodeficiencies , Inborn errors of Immunity

Research Area: Genomics , Host-Pathogen Interactions , Molecular Pathology