Yi Ren
Vanderbilt Center for Structural Biology (CSB)
Fully processed eukaryotic mRNAs are exported to the cytoplasm where translation occurs. We determine the sequence and mechanism of events that prepare nuclear mRNA for export and investigate how mRNA export is altered in human disease.
Fully processed eukaryotic mRNAs are exported to the cytoplasm where translation occurs. We determine the sequence and mechanism of events that prepare nuclear mRNA for export and investigate how mRNA export is altered in human disease.
Keywords: nuclear mRNA export , virus infection , mRNA binding protein , Cyro-EM , X-ray crystallography
Research Area: Structural Biology , RNA Biology , Virology , Molecular Pathology