Past Science Hours

October 18, 2017
Note: Room change to PRB 206
Systems based analysis of melanoma after targeted therapy reveal loss of neural crest identity and MHC I as potential therapeutic opportunities
Deon Doxie, Graduate Student, Irish Laboratory
From patients to cell biology and back: using cytometry to reveal relationships between the stem cell niche and brain tumors
Rebecca Ihrie Ph.D. Assistant Professor, Cell & Developmental Biology

October 4, 2017
Understanding Outcomes following Stem Cell Transplant for Hematologic Malignancies: A Machine Learning Approach
Jocelyn Gandelman, Medical Student, Irish & Jagasia Laboratories
Breast cancer dormancy: What’s bone got to do with it?
Rachelle Johnson Ph.D., Assistant Professor, Medicine

September 27, 2017
The role of TGF-B responsive myeloid cell in tumor-induced bone disease.
Denise Buenrostro, Graduate Student, Sterling Lab
Translational Immuno-oncology research: identifying new combinations for the treatment of cancer
Justin M. Balko, Pharm.D. Ph.D, Assistant Professor, Department of Medicine, VUMC
Leader of Molecular Oncology, Center for Cancer-Targeted Therapies

Wed, 04/19/2017 – 4:00pm
Investigating the role of EphA2 in anti-tumor immunity mediated through PD-L2 in NSCLC
Eileen Shiuan, Graduate Student, (Chen Lab)
PRB 898J
Exosome secretion in stromal matrix assembly and organization
Merlyn Emmanuel, Post-doctoral Fellow (Weaver Lab)

Wed, 04/12/2017 – 4:00pm
Mapping cell state transitions from single-cell data: implications for cancer stem cells
Ken S. Lau PhD, Assistant Professor of Cell and Developmental Biology
PRB 898J
Faculty Presentation

Wed, 04/05/2017 – 4:00pm
No Science Hour- Week of AACR Annual Meeting
PRB 898J

Wed, 03/29/2017 – 4:00pm
Dissecting MET expression and activity during therapy in human glioblastoma tumors
Justine Sinnaeve, Graduate Student (Ihrie Lab)
PRB 898J
A molecular simulation study of the physical properties of cardiolipin containing lipid bilayers
Blake Wilson, Post-doctoral Fellow (Lopez Lab)

Wed, 03/22/2017 – 4:00pm
The USP46 deubiquitinase complex promotes Wnt signaling by blocking Wnt receptor turnover
Victoria Ng, Graduate Student (Lee Lab)
PRB 206
Role of exosomal endoglin in filopodia and tumor cell motility
Caitlin McAtee, Post-doctoral Fellow (Weaver Lab)

Wed, 03/15/2017 – 4:00pm
Mechanical and Structural Control of Tumor Angiogenesis and Metastasis
Cynthia Reinhart-King PhD, Professor of Biomedical Engineering
PRB 898J
Faculty Presentation

Wed, 03/08/2017 – 4:00pm
Targeting Gli2 in Tumor-Induced Bone Disease
Kristin Kwakwa, Graduate Student (Sterling Lab)
PRB 898J
BVES modulation of intestinal homeostasis and tumorigenesis via regulation of WNT signaling
Joshua Thompson, Graduate Student (Williams Lab)

Wed, 03/01/2017 – 4:00pm
Role of Exosome Secretion in Cancer Cell Motility
Bong Hwan Sung, Research Assistant Professor, Cancer Biology
PRB 898J
Cancer Biology Research Faculty Highlight

Wed, 02/22/2017 – 4:00pm
Targeting mLST8 in mTORC2-dependent lung cancer
Laura Kim, Graduate Student
PRB 898J
Insights into Kinase Fusion Biology: Does the Fusion Partner Matter?
Merrida Childress (Graduate Student, Lovly Lab)

Wed, 02/15/2017 – 4:00pm
Positional Identity Corresponds to Differential mTORc1 Activity between Subdomains of the Mouse Ventricular-Subventricular Zone
Gabrielle Rushing, (Graduate Student, Ihrie Lab)
PRB 898J
The role of HNSCC-derived exosomes in driving tumor progression
Shinya Sato, Post-Doctoral Fellow (Weaver Lab)

Wed, 02/08/2017 – 4:00pm
RSK2 controls homeostasis of the mammary ER+ population
Zach Sandusky (Graduate Student, Lannigan Lab)
PRB 898J
A web application for optimal selection of adaptive designs in phase I oncology clinical trials
Sheau-Chiann Chen (Postdoctoral Fellow, Shyr Lab)

Wed, 02/01/2017 – 4:00pm
A brief departure into glutamine metabolism and T cells
Marc Johnson, Graduate Student (Rathmell Lab)
PRB 898J
Progress Towards Automated, Robust, High-Throughput Drug Screening
Alex Lubbock, Post-Doctoral Fellow (Lopez Lab)

Wed, 01/25/2017 – 4:00pm
EGFR rearrangements in NSCLC
Jean-Nicolas Gallant (Graduate Student)
PRB 898J
Bet hedging as a survival strategy in oncogene-addicted cancer
Leonard Harris, Post-Doctoral Fellow (Lopez Lab)

Wed, 01/18/2017 – 4:00pm
Was Warburg Right?—Lessons from Leukemic and Activated T Cells
Jeff Rathmell, Ph.D. Cornelius Vanderbilt Professor of Immunobiology Pathology, Microbiology, and Immunology Cancer Biology Director, Vanderbilt Center for Immunobiology
PRB 206
Faculty Presentation

Wed, 12/14/2016 – 4:00pm
Winter Break. Happy Holidays!!! See Everyone Next Year!!
PRB 898J

Wed, 12/07/2016 – 4:00pm
Bone Morphogenetic Proteins (BMPs) and their role in cancer
Phil Owens, Research Assistant Professor
PRB 898J
Research Faculty Highlight

Wed, 11/30/2016 – 4:00pm
Only one speaker this week.
PRB 898J
Loss of Activin Receptor Type IB induces head and neck squamous cell carcinoma invasion
Holli Ann Loomans (Graduate Student, Andl&Zijlstra Laboratories)

Wed, 11/23/2016 – 4:00pm
No Science Hour
Happy Thanksgiving!!!
PRB 898J

Wed, 11/16/2016 – 4:00pm
David Wooten (Graduate Student, Quaranta Lab)
PRB 898J
Endocrine Resistance in ER+ Metastatic Breast Cancer
Miranda Sowder (Graduate Student, Lannigan Lab)

Wed, 11/09/2016 – 4:00pm
Prioritize candidate gene set by using fuzzy measure in rare disease case study
YuLin Dai, Post-doctoral Fellow (Shyr Lab)
PRB 898J
Only one speaker this week.

Wed, 11/02/2016 – 4:00pm
FoxO transcription factor regulation and function in C. elegans
Patrick Hu, M.D., Ph.D. Associate Professor of Medicine, Cell and Developmental Biology, and Cancer Biology
PRB 898J
Faculty Presentation

Wed, 10/26/2016 – 4:00pm
Stem Cell Diversity in Glioblastoma
Nalin Leelatian (Graduate Student, Irish Lab)
PRB 898J
Targeting Mcl-1 in luminal breast cancers to improve patient outcome
Michelle Williams (Graduate Student, Cook Lab)

Wed, 10/19/2016 – 4:00pm
Can we reconstitute the human tumor microenvironment in vivo?
Young Jun Kim, M.D., Ph.D., Associate Professor of Otolaryngology and co-leader of the Translational Research and Interventional Oncology Research Program
PRB 898J
Faculty Seminar

Wed, 10/12/2016 – 4:00pm
The Discrepancy among Single Nucleotide Variants Detected by DNA and RNA High Throughput Sequencing Data
Shilin Zhao, Ph.D. (Postdoctoral Fellow, Shyr Lab)
PRB 898J
Lizandra Jimenez, Post-Doctoral Fellow (Weaver Lab)

Wed, 10/05/2016 – 4:00pm
Multi-Perspective Quality Control of Illumina RNA Sequencing Data Analysis
Quanhu Sheng, Research Assistant Professor (Shyr Lab)
PRB 898J
A computational approach to infer the cellular response to an unknown toxin
James Pino, Graduate Student (Lopez Lab)

Wed, 09/28/2016 – 4:00pm
Proteolytic processing of ALCAM regulates metastasis
Katie Hebron (Graduate Student, Zijlstra Lab)
PRB 898J
High Content Dissection of Human Melanoma Tumor Heterogeneity During Targeted Therapy
Deon Doxie (Graduate Student, Irish Lab)

Wed, 09/21/2016 – 4:00pm
The Role of TGF-β Responsive Myeloid Cells in Tumor-Induced Bone Disease
Denise Buenrostro (Graduate Student, Sterling Lab)
PRB 898J
A non-quiescent idling state in drug-treated BRAF-mutated melanoma cells
Bishal Paudel (Graduate Student, Quaranta Lab)

Wed, 09/14/2016 – 4:00pm
Bitter(sweet) Death: How Over-Reliance On Glycolysis Attenuates Proliferation
Keisha Hardeman, Graduate Student (Fessel&Quaranta Labs)
898J PRB
Adrenergic Signaling in Osteoblasts Alters Bone Marrow Vasculature: Implications for Breast Cancer Bone Metastasis
Patrick Mulcrone, Graduate Student, (Elefteriou&Sterling Labs)

Wed, 05/04/2016 – 12:15pm
TBA

Wed, 04/27/2016 – 4:00pm
In depth Characterization of Follicular Lymphoma Tumor Cells by Mass Cytometry
Cara Wogsland, (Graduate Student, Irish Lab)
898 PRB J
Only one speaker this week.

Wed, 04/20/2016 – 4:00pm
No Science Hour
AACR Annual Meeting Week
898 PRB J

Wed, 04/13/2016 – 4:00pm
Modeling mTOR-driven Brain Tumor Development in Tuberous Sclerosis Complex
Gabrielle Rushing, (Graduate Student, Ihrie Lab)
PRB 206
Targeted Inhibition of Doxorubicin Cardiotoxicity
Zach Sandusky (Graduate Student, Lannigan Lab)

Wed, 04/06/2016 – 4:00pm
Novel Treatment Modalities for Retinoblastoma: Animal Models for Drug Development
Anthony B. Daniels, M.D., M.Sc., Director of Ocular Oncology, Assistant Professor of Ophthalmology & Visual Sciences, Cancer Biology, and Radiation Oncology
898 PRB J
Faculty Seminar

Wed, 03/30/2016 – 4:00pm
Mechanistic Insights into ALK Fusion Biology Through Investigation of the Fusion Partner
Merrida Childress (Graduate Student, Lovly Lab)
898 PRB J
EGFR rearrangements in NSCLC
Jean-Nicolas Gallant (Graduate Student)
Wed, 03/23/2016 – 4:00pm
Single cell analysis of human tissues and solid tumors with mass cytometry
Nalin Leelatian (Graduate Student, Irish Lab)
898 PRB J
NRSA – a comprehensive tool for reliable analysis of GRO/PRO-seq data
Jing Wang (Post-Doctoral Fellow, Shyr Lab)
Wed, 03/16/2016 – 4:00pm
Tumor cell heterogeneity: Form and function
Darren Tyson, Research Assistant Professor, Cancer Biology
898 PRB J
Special Research Faculty presentation Highlight
Wed, 03/09/2016 – 4:00pm
Development of defined culture conditions for recapitulating breast cancer subtypes in vitro
Miranda Sowder (Graduate Student, Lannigan Lab)
898 PRB J
A systems-level approach to Small-Cell Lung Cancer heterogeneity
David Wooten (Graduate Student, Quaranta Lab)
Wed, 03/02/2016 – 4:00pm
The Way Wnt Works: Mechanism of Wnt Signal Transduction
Ethan Lee, MD, PhD, Professor of Cell and Developmental Biology
898 PRB J
Faculty Seminar
Wed, 02/24/2016 – 4:00pm
ACVRIB-dependent Activin A signaling regulates esophageal and head and neck squamous cell carcinoma progression
Holli Ann Loomans (Graduate Student, Andl&Zijlstra Laboratories)
898 PRB J
Rapid mTOR-dependent Mcl-1 translation limits therapeutic efficacy of ABT-263 in breast cancers
Michelle Williams (Graduate Student, Cook Lab)
Wed, 02/17/2016 – 4:00pm
Innovative Translational Research Shared Resource-Bi-directional translation between the clinic and the bench
Kim Dahlman, Research Assistant Professor, Cancer Biology
898 PRB J
Role of exosome secretion in directional cancer cell migration in vivo
Bong Hwan Sung, Research Assistant Professor, Cancer Biology
Wed, 02/10/2016 – 4:00pm
Translational Studies in Renal Cell Carcinoma
W. Kimryn Rathmell, Ph.D., M.D., Director, Division of Hematology Oncology, Professor of Clinical Medicine and Cancer Biology
898 PRB J
Faculty Seminar
Wed, 02/03/2016 – 4:00pm
Only one speaker this week.
898 PRB J
Characterizing cell subsets in heterogeneous tissues using marker enrichment modeling
Kirsten Diggins (Graduate Student, Irish Lab)
Wed, 01/27/2016 – 4:04pm
Non-inferiority Test Procedures with Multiple Reference Treatments
Li-Ching Huang, Post-Doctoral Fellow (Shyr Lab)
TGF-β’s Role in Myeloid Regulation of Tumor-Induced Bone Disease
Denise Buenrostro (Graduate Student, Sterling Lab)
Wed, 01/20/2016 – 4:00pm
Inferring Directed Protein Networks from Human Tumors
Alex Lubbock, Post-Doctoral Fellow (Lopez Lab)
898 PRB J
MDM2 inhibition counteracts therapy-induced genomic instability in melanoma cells
Anna Vilgelm, Research Assistant Professor (Richmond Lab)
Wed, 01/13/2016 – 4:00pm
Heterogeneity and complex drug response dynamics in BRAF-mutated melanoma cells
Bishal Paudel (Graduate Student, Quaranta Lab)
898 PRB J
Linking Dysregulated Cellular Metabolism To Therapeutic Response in BRAF-mutated Melanomas
Keisha Hardeman (Graduate Student, Fessel&Quaranta Labs)
Wed, 01/06/2016 – 8:02am
Understanding Resistance to Mutation Targeted Therapies and the Evolving Immune Microenvironment
Jeffrey Sosman MD; Professor of Medicine, Director, Melanoma and Tumor Immunotherapy Program
Faculty Seminar
Wed, 12/23/2015 – 4:00pm
No Science Hour.
Winter Break. See you next Year!!
898 PRB J
Wed, 12/16/2015 – 4:00pm
Anna Vilgelm, Post-Doctoral Fellow (Richmond Lab)
898 PRB J
Akshata Udvayar, Post-Doctoral Fellow (Quaranta Lab)
Wed, 12/09/2015 – 4:00pm
Exosome secretion is enhanced by the PI3K signaling pathway in Head and Neck cancer
Selma Maacha, Post-Doctoral Fellow (Weaver Lab)
898 PRB J
The proteolytic processing of ALCAM regulates metastasis
Katie Hebron (Graduate Student, Zijlstra Lab)
Wed, 12/02/2015 – 4:00pm
Optical imaging of tumor heterogeneity
Melissa Skala PhD, Assistant Professor Biomedical Engineering & Cancer Biology
898 PRB J
Faculty Presentation
Wed, 11/25/2015 – 4:00pm
No Science Hour
"Thanksgiving Break"
898 PRB J
Wed, 11/18/2015 – 4:00pm
Targeting the BMP pathway in breast cancer and the tumor microenvironment
Philip Owens, Research Assistant Professor (Richmond Lab)
898 PRB J
Special Cancer Biology Research Faculty Spotlight
Wed, 11/11/2015 – 4:00pm
KEGGprofile: Analyzing and Visualizing high dimensional data in KEGG pathway
Shilin Zhao, Post-Doctoral Fellow (Shyr Lab)
898 PRB J
Sympathetic Activation Alters the Bone Vasculature: Implication for Osteotropic Breast Cancer Metastasis
Patrick Mulcrone (Graduate Student, Elefteriou Lab)
Wed, 11/04/2015 – 4:00pm
mTOR & friends: Standing at the crossroads of immunity & cancer to relay signals
Mark Boothby, M.D., Ph.D., Professor of Pathology, Microbiology, and Immunology
898 PRB J
Faculty Seminar
Wed, 10/28/2015 – 4:00pm
Mechanisms Controlling Bony Invasion in Oral Squamous Cell Carcinoma
Shellese Cannonier (Graduate Student, Sterling Lab)
898 PRB J
High content dissection of human melanoma tumor heterogeneity during treatment using mass cytometry
Deon Doxie (Graduate Student, Irish Lab)
Wed, 10/21/2015 – 4:00pm
Role of Kaiso and its interacting partners in tumorigenesis
Manish Tripathi, Research Instructor Reynolds Lab
898 PRB J
Somatic Mutation Calling Using Both DNAseq and RNAseq Data
Quanhu Sheng, Research Assistant Professor (Shyr Lab)
Wed, 10/14/2015 – 4:00pm
Big Data in Top Medical Journals: Quantitative Biology for Reproducible Research and Publishing with Integrity
Yu Shyr Ph.D., Director, Vanderbilt Center for Quantitative Sciences
898 PRB J
Faculty Seminar
Wed, 10/07/2015 – 4:00pm
Cortactin promotes tumor progression via exosome secretion
Seema Sinha (Graduate Student Weaver Lab)
898 PRB J
Regulation of tumor metabolism by ephrin-A1 and EphA2 in a HER2/Neu-positive breast cancer model
Victoria Youngblood, Graduate Student (Chen Lab)
Wed, 09/30/2015 – 4:00pm
THE IL4/IL4 RECEPTOR SIGNALING AXIS PROMOTES BREAST AND COLON TUMOR GROWTH AND METASTASIS
Kate Venmar, Graduate Student (Fingleton Lab)
898 PRB J
An unbiased metric of anticancer drug effect in vitro
Leonard Harris, Post-Doctoral Fellow (Lopez Lab)
Wed, 09/23/2015 – 4:00pm
Enhanced lung cancer progression resulting from non-canonical NF-κB signaling via p52
Jamie Ausborn (Graduate Student, Blackwell Lab)
PRB 898 J
Manipulating the senescence associated secretory phenotype to reinforce tumor suppression in melanoma
Jeffrey Pawlikowski, Post-Doctoral Fellow (Richmond Lab)
Wed, 09/16/2015 – 4:00pm
Helicobacter pylori suppresses inflammation via type IV secretion system mediated DNA translocation
Matthew Varga (Graduate Student, Peek Lab)
PRB 898 J
The Role of NF-kB in BPH
David Austin (Graduate Student, Hayward Lab)
Wed, 09/09/2015 – 4:00pm
Neutrophil-derived IL-1β impairs efficacy of NF-κB inhibitors against lung cancer
Allyson McLoed (Graduate Student, Blackwell Lab)
PRB 898 J
Identification of isoketal-modified proteins and genes that regulate their formation
Stacey Mont (Graduate Student, Freeman Lab)
Wed, 04/29/2015 – 4:00pm
Ras-Erk signaling controls localization of Argonaute2 (Ago2) to late endosomes and secretion into exosomes
Andrew McKenzie (Post-doctoral Fellow, Weaver Lab)
PRB 898 J
Comprehensive evaluation of adaptive designs for phase I oncology clinical trials
Sheau-Chiann Chen (Postdoctoral Fellow, Shyr Lab)
Wed, 04/22/2015 – 4:00pm
No Science Hour– AACR Week
PRB 898 J
Wed, 04/15/2015 – 4:40pm
Disrupted cooperation between transcription factors across diverse cancer types
Jing Wang (Postdoctoral Fellow, Shyr Lab)
PRB 898 J
Activin A is a novel regulator of the esophageal microenvironment
Holli Ann Loomans (Graduate Student, Andl Lab)
Wed, 04/08/2015 – 4:00pm
Characterizing glioblastoma stem cell identity and signaling with single cell biology
Nalin Leelatian (Graduate Student, Irish Lab)
PRB 898 J
The Role of Myeloid-Tumor Cell Interactions in Tumor-Induced Bone Disease
Denise Buenrostro (Graduate Student, Sterling Lab)
Wed, 04/01/2015 – 4:00pm
Neutrophil entrainment to increase tumor cell killing to prevent breast cancer metastasis
Nicole Lavender (Postdoctoral Fellow, Richmond Lab)
PRB 898 J
Dissecting Myeloid derived suppressive cells (MDSCs) in high-grade B-cell lymphoma (DLBCL)
Mikail Roussel (Visiting Research Fellow from University of Rennes, France. Irish Lab)
Wed, 03/25/2015 – 4:00pm
Transcriptional regulatory networks drive epigenetic heterogeneity in small cell lung cancer
David Wooten (Graduate Student, Quaranta Lab)
PRB 898 J
Regulation of centrosome integrity by the Ser/Thr kinase, ERK8, and its potential role in TNBC
Miranda Sowder (Graduate Student, Lannigan Lab)
Wed, 03/18/2015 – 4:00pm
Molecular Metabolism and Redox Biology in Complex Disease
Joshua Fessel MD PhD, Assistant Professor of Medicine and Pharmacology
PRB 898 J
Wed, 03/11/2015 – 4:00pm
Mcl-1-Mediated Resistance to ABT-263 is Combated by mTOR inhibition in Luminal Breast Cancers
Michelle Williams (Graduate Student, Cook Lab)
PRB 898 J
Which markers matter? Population contribution index (PCI) quantifies feature enrichment on sample subsets
Kirsten Diggins (Graduate Student, Irish Lab)
Wed, 03/04/2015 – 4:00pm
BVES is an essential regulator of intracellular signaling in inflammatory carcinogenesis
Bobak Parang (Graduate Student, Williams Lab)
PRB 898 J
Defining Metabolic Heterogeneity In BRAF-mutated Melanoma
Keisha Hardeman (Graduate Student, Quaranta Lab)
Wed, 02/25/2015 – 4:00pm
Cell Polarity, Stem Cells and Breast Cancer
Ian Macara PhD (Chair Dept Cell & Developmental Biology)
PRB 898 J
Wed, 02/18/2015 – 4:00pm
Drug Response Heterogeneity in BRAF-mutated melanoma cell lines treated with targeted therapies
Bishal Paudel (Graduate Student, Quaranta Lab)
PRB 898 J
Investigating ALCAM proteolysis in prostate cancer progression: A multi-dimensional approach
Katie Hebron (Graduate Student, Zijlstra Lab)
Wed, 02/11/2015 – 4:00pm
Chronic Sympathetic Nervous System Activation Alters the Abundance of Bone Vasculature, Potentially Promoting Breast Cancer Metastasis
Patrick Mulcrone (Graduate Student, Elefteriou Lab)
PRB 898 J
Inactivating the EWS/FLI1 transcription factor with PM01183
Matthew Harlow (Graduate Student, Grohar Lab)
Wed, 02/04/2015 – 4:00pm
Bobak Parang (Graduate Student, Williams Lab)
PRB 898 J
Catherine Meador (Graduate Student, Pao Lab)
Wed, 01/28/2015 – 4:00pm
Only one speaker this week.
PRB 898 J
'High content dissection of human melanoma tumor heterogeneity during treatment using mass cytometry
Deon Doxie (Graduate Student, Irish Lab)
Wed, 01/21/2015 – 4:00pm
NFkB-mediated leukocyte recruitment modulates drug response in melanoma
Anna Vilgelm, Ph.D. (Postdoctoral Fellow, Richmond Lab)
PRB 898 J
Hh and TGFB signaling converge on Gli2 to control bony invasion and bone destruction in OSCC via PTHrP
Shellese Cannonier (Graduate Student, Sterling Lab)
Wed, 01/14/2015 – 4:00pm
Rictor-dependent mTOR signaling in breast cancers
Meghan Morrison (Graduate Student, Cook Lab)
PRB 898 J
Ephrin-A1 regulates breast tumorigenesis via regulation of the metabolic landscape
Victoria Youngblood (Graduate Student, Chen Lab)
Wed, 01/07/2015 – 4:00pm
CAR T cells as a therapy for hematologic malignancies: past, present, and future
Marco Davila MD/PhD
PRB 898 J
Wed, 12/10/2014 – 4:00pm
Role of Single-Stranded Binding Proteins in Head and Neck Carcinoma
Elizabeth Simonik (Graduate Student, Brandt Lab)
PRB 898 J
Intrinsic stochasticity and heterogeneous drug response in cancer cell populations
Leonard Harris (Post-doctoral Fellow, Lopez Lab)
Wed, 12/03/2014 – 4:00pm
Heterogeneity of Small-Cell Lung Cancer phenotypic states driven by distinct transcriptional programs
Akshata Udvayar (Graduate Student, Quaranta&Massion Labs)
PRB 898 J
The role of TLR9 in H. pylori mediated parthenogenesis
Matthew Varga (Graduate Student, Peek Lab)
Wed, 11/19/2014 – 4:00pm
Expression of IL4R determines function of IL13 in survival and chemoresistance, of colon cancer cells
Miranda Hallet (Post-doctoral Fellow, Fingleton Lab)
PRB 898 J
IL4 Receptor α mediates enhanced glucose and glutamine metabolism to support breast cancer growth
Kate Venmar (Graduate Student, Fingleton Lab)
Wed, 11/12/2014 – 4:00pm
Anti-estrogens control ERK1/2-RSK2 signaling via regulation of RSK2 subcellular localization
Deborah Lannigan PhD, Dept. of Pathology, Microbiology and Immunology
PRB 206
Wed, 11/05/2014 – 4:00pm
Cortactin, a key regulator of tumor progression, promotes exosome secretion
Seema Sinha (Graduate Student, Weaver Lab)
PRB 898 J
ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of driver-negative melanoma
Katherine Hutchinson (Graduate Student, Pao Lab)
Wed, 10/29/2014 – 4:00pm
Manipulating senescence to combat melanoma initiation and progression
Jeffrey Pawlikowski (Post-doctoral Fellow, Richmond Lab)
PRB 206
The role of Hhex in normal and malignant lymphoid development
Charnise Goodings (Graduate Student, Dave Lab)
Wed, 10/22/2014 – 4:00pm
The role of MMP13 on tumor development in the liver microenvironment
Alisha Mendonsa (Graduate Student, Gorden Lab)
PRB 206
Epithelial alternative NF-kappaB signaling promotes inflammation and lung cancer
Jamie Ausborn (Graduate Student, Blackwell Lab)
Wed, 10/15/2014 – 4:00pm
Molecular Engineering of Polymeric Nanoparticles for Immunomodulation
John T. Wilson PhD, Chemical and Biomolecular Engineering
PRB 206
TBA
Wed, 10/08/2014 – 4:00pm
PI(3,5)P2 controls branched actin dynamics at late endosomes by regulating cortactin-actin interactions
Nan Hyung Hong (Graduate Student, Weaver Lab)
PRB 206
Identification of Isoketal adducted proteins involved in oxidative stress
Stacey Mont (Graduate Student, Freeman Lab)
Wed, 10/01/2014 – 4:00pm
NF-kB Stimulates Androgen Receptor Variant Expression in Human BPH
David Austin (Graduate Student, Hayward Lab)
PRB 206
NF-κB inhibition in myeloid cells promotes lung tumorigenesis through production of IL-1β
Allyson McLoed (Graduate Student, Blackwell Lab)
Wed, 09/24/2014 – 4:00pm
Neuregulin signaling in development of the luminal breast epithelium
David Vaught (Post-doctoral Fellow, Cook Lab)
PRB 206
Genetic and pharmacologic inhibition of EPHA2 in KRAS and EGFR mutant non-small cell lung cancer
Katherine Amato (Graduate Student, Chen Lab)
Wed, 09/17/2014 – 4:00pm
Elucidating the Role of MicroRNAs in Retinoblastoma Progression
Nikia Laurie PhD, Assistant Professor, Cancer Biology and Epigenomics Program; Eloise and Warren Batts Research Scholar Director, Retinoblastoma Center of Excellence; Stanley Manne Children's Research Institute; Northwestern University Feinberg School of Medicine
PRB 898 J
Wed, 09/10/2014 – 4:00pm
Linking patient outcome to high throughput protein expression data reveals novel drivers of colorectal adenocarcinoma.
Christi French (Graduate Student, Weaver Lab)
PRB 898 J
Getting Back in Shape: An unmasked role of p120/E-cadherin in epithelial form and function
Huapeng Yu (Graduate Student, Reynolds Lab)
Wed, 09/03/2014 – 4:00pm
Role of stromal MMP2 in breast cancer metastasis
Andreia Bates, Graduate Student (Fingleton Lab)
PRB 898 J
Meeting with Graduate Students at 4:30 pm
Wed, 05/14/2014 – 4:00pm
Activating PIK3CA mutations induce an EGFR/ERK paracrine signaling axis in basal-like breast cancer
Christian Young, PhD (Post-Doctoral Fellow, Arteaga&Cook Laboratories)
PRB 898 J
Identifying mechanisms of resistance to combined inhibition of HER2 and PI3K in HER2+/PIK3CA-mutant breast cancer
Ariella Hanker, PhD (Post-Doctoral Fellow, Arteaga Laboratory)
Wed, 05/07/2014 – 4:00pm
Investigating Modulators of Bone Destruction in Oral Squamous Cell Carcinoma
Shellese Cannonier (Graduate Student, Sterling Lab)
PRB 898 – J
Quantifying Erlotinib Response Heterogeneity for Biomarker and Target Discovery in NSCLC
Katherine Jameson, Ph.D. (Postdoctoral Fellow, Quaranta&Yankeelov Labs)
Wed, 04/30/2014 – 4:00pm
Single Cell Systems Biology Approach to Dissecting Melanoma
Deon Doxie (Graduate Student, Irish Lab)
PRB 898 – J
TBA
Only one speaker this week.
Wed, 04/23/2014 – 4:00pm
Targeting EWS/FLI1 transcriptional activity with PM01183, an analog of Trabectedin
Matthew Harlow (Graduate Student, Grohar Lab)
PRB 898 – J
Investigating Tumor Heterogeneity with Fluorescent Barcoding
Katie Hebron (Graduate Student, Zijlstra Lab)
Wed, 04/16/2014 – 4:00pm
Optimizing sequential anti-EGFR treatment in EGFR-mutant lung cancer
Catherine Meador (Graduate Student, Pao Lab)
PRB 898 – J
Exosome secretion at membrane protrusions drive invasive behavior
Daisuike Hoshino, Ph.D. (Postdoc, Weaver Lab)
Wed, 04/09/2014 – 4:00pm
No Science Hour AACR Week
Wed, 04/02/2014 – 4:00pm
MDM2 and Aurora kinase A inhibitors synergize to block melanoma growth by inducing tumor cell death and immune clearance
Anna Vilgelm, Ph.D. (Postdoctoral Fellow, Richmond Lab)
PRB 898 – J
Sample size estimation and gene expression visualization: two tools for RNA sequencing data analysis
Shilin Zhao, Ph.D. (Postdoctoral Fellow, Shyr Lab)