Verra Ngwa, Ph.D
Postdoctoral Fellow, Chen Lab
Research Description:
Verra’s research focuses on glutamine metabolism in HER2 amplified and triple-negative breast cancer (TNBC), and how glutaminolysis in cancer cells affect tumor immunity.
Publications:
Verra Ngwa, Deanna Edwards, Yoonha Hwang, et al. ” Loss of vascular endothelial glutaminase inhibits tumor growth and metastasis, and increases sensitivity to chemotherapy” Cancer Research Communication. June 29, 2022.
Ngwa VM, Edwards DN, Philip M, Chen J “Microenvironmental Metabolism Regulates Antitumor Immunity” Cancer Research. 2019 Aug 15;79(16)
Deanna N. Edwards, Verra M. Ngwa, Shan Wang, Eileen Shiuan, Dana Brantley-Sieders, Laura C. Kim, Albert B. Reynolds, and Jin Chen (2017) “ Regulation of cancer glutamine metabolism by EphA2 RTK-dependent activation of transcriptional co-activators YAP and TAZ,” Cell Signaling. PMCID:29208682
Ngwa, Verra M.; Axford, David S.; Healey, Allison N.; Nowak, Scott J.; Carol A. Chrestensen; Jonathan L. McMurry (2017) “A versatile cell-penetrating peptide-adaptor system for efficient delivery of molecular cargos to subcellular destinations,’’ PLOS ONE. PMCID: PMC5446193.
Salerno, J.C, Ngwa, V.M, Nowak, S.J, Chrestensen, C.A and McMurry, J.L., (2016) ‘’Novel cell-penetrating peptide-adaptors effect intracellular delivery and endosomal escape of protein cargos,” Journal of Cell Science. PMCID: PMC4813321.
Hiroshi Qadotaa , Olga Mayansb , Jonathan L. McMurry , Yohei Matsunagaa , Kristy J. Wilsona , Grace E. Kwona , Rachel Stanforda , Kevin Deehana , Tina L. Tinleya , Verra M. Ngwa and Guy M. Beniana (2016) “The SH3 domain of UNC-89 (obscurin) interacts with paramyosin, a coiled-coil protein, in C. elegans muscle,” Molecular Biology of the Cell. PMCID: PMC4865318.
Hiroshi Qadotaa , Olga Mayansb , Jonathan L. McMurry , Yohei Matsunagaa , Kristy J. Wilsona , Grace E. Kwona , Rachel Stanforda , Kevin Deehana , Tina L. Tinleya , Verra M. Ngwa and Guy M. Beniana (2016) “The SH3 domain of UNC-89 (obscurin) interacts with paramyosin, a coiled-coil protein, in C. elegans muscle,” Molecular Biology of the Cell. PMCID: PMC4865318.