Publications
RECENT VANDERBILT FACULTY AND TRAINEES PUBLICATIONS:
Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia. Cancer Res. 2024 Apr 1;84(7):1101-1114. Haley Ramsey, Alexander Silver, Jeffrey Rathmell, Michael Savona, et al.
Multiparametric Single-Vesicle Flow Cytometry Resolves Extracellular Vesicle Heterogeneity and Reveals Selective Regulation of Biogenesis and Cargo Distribution. ACS Nano. 2024 Apr 5. Von Lersner AK, Sung BH, Wilson JT, Irish JM, Weaver AM, Zijlstra A. et al.
A Cancer Nanovaccine for Co-Delivery of Peptide Neoantigens and Optimized Combinations of STING and TLR4 Agonists. ACS Nano. 2024 Mar 5;18(9):6845-6862. Bharti V, Joyce S, Wilson JT, et al.
Cell-type-specific and disease-associated expression quantitative trait loci in the human lung. Nat Genet. 2024 Mar 28. Flaherty DK, Blackwell TS, et al.
The mitochondrial fission protein DRP1 influences memory CD8+ T cell formation and function. J Leukoc Biol. 2024 Mar 29;115(4):679-694. Stevens MG, Mason FM, et al.
Multiomic Profiling of Human Clonal Hematopoiesis Reveals Genotype and Cell-Specific Inflammatory Pathway Activation. Blood Adv. 2024 Mar 20. Heimlich JB, Bhat P, Silver AJ, Savona MR, Bick AG, Ferrell PB Jr, et al.
Tumor therapy by targeting extracellular hydroxyapatite using novel drugs: A paradigm shift. Cancer Med. 2024 Feb;13(3):e6812. Tantawy MN, McIntyre JO, Yull F, Rhoades J, McCawley LJ, Fingleton B, et al.
Polygenic risk score for ulcerative colitis predicts immune checkpoint inhibitor-mediated colitis. Nat Commun. 2024 Mar 26;15(1):2568. Johnson DB, Lovly CM, Balko JM, Aldrich MC, et al.
The Hallmarks of Precancer. Cancer Discov. 2024 Apr 4;14(4):683-689. Glass SE, Coffey RJ, Lau KS, et al.
Vaccination generates functional progenitor tumor-specific CD8 T cells and long-term tumor control. bioRxiv [Preprint]. 2024 Feb 29:2024. Detrés Román CR, Roetman JJ, Philip M, et al.
PTHrP intracrine actions divergently influence breast cancer growth through p27 and LIFR. Breast Cancer Res. 2024 Feb 26;26(1):34. Edwards CM, Kane JF, Smith JA, Grant DM, Karno BA, Johnson RW, et al.
Distinct roles for interleukin-23 receptor signaling in regulatory T cells in sporadic and inflammation-associated carcinogenesis. Front Oncol. 2024 Feb 5;13. Jacobse J, Pilat JM, Li J, Brown RE, Choksi YA, Williams CS, Markham NO, Short SP, Goettel JA, et al.
Atezolizumab in Combination With Carboplatin and Survival Outcomes in Patients With Metastatic Triple-Negative Breast Cancer: The TBCRC 043 Phase 2 Randomized Clinical Trial. JAMA Oncol. 2024 Feb 1;10(2):193-201. Lehmann BD, Abramson VG, Habing An, Gonzalez-Ericsson PI, Sanders ME, Abramson RG, Shyr Y, Pietenpol JA, et al.
Transcriptomic analysis of benign prostatic hyperplasia identifies critical pathways in prostatic overgrowth and 5-alpha reductase inhibitor resistance.
Prostate. 2024 Apr;84(5):441-459. Jin R, Forbes CM, Miller NL, Case T,
Distinct roles for interleukin-23 receptor signaling in regulatory T cells in sporadic and inflammation-associated carcinogenesis. Front. Oncol., 04 February 2024. Justin Jacobse, Jennifer Pilat, Jing Li, Rachel Brown, Yash Choksi, Christopher Williams, Nicholas Markham, Sarah Short, Jeremy Goettel, et al.
NKG2A Is a Therapeutic Vulnerability in Immunotherapy Resistant MHC-I Heterogeneous Triple-Negative Breast Cancer. Cancer Discov. 2024 Feb 8;14(2):290-307. Taylor BC, Sun X, Opalenik SR, Hanna A, Chou ST, Lehmann BD, Abramson VG, Pietenpol JA, Balko JM, et al.
Find Adapt: A python package for fast and accurate adapter detection in small RNA sequencing. PloS Comput Biol. 2024 Jan 22; 20 (1):e1011786. Hua-Chang Chen, Jing Wang, Yu Shyr, Qi Liu
Genomic dissection and mutation-specific target discovery for breast cancer PIK3CA hotspot mutations. bioRxiv. Preprint. 2024 Jan 4. Adam X. Miranda, Brad Davidson, Sarah Croessmann, Ben H. Park, Emily Hodges, et al.
Tumor therapy by targeting extracellular hydroxyapatite using novel drugs: A paradigm shift. Cancer Med. 2024 Jan 18. Mohammed N Tantawy, J Oliver McIntyre, Fiona Yull, Julie Rhoades, Lisa McCawley, Barbara Fingleton, et al.
Endogenous pAKT activity is associated with response to AKT inhibition alone and in combination with immune checkpoint inhibition in murine models of TNBC. Cancer Letters, 2024 Feb 2:216681. Kennady K. Bullock, Rebecca Shattuck-Brandt, Carly Scalise, Weifeng Luo, Sheau-Chiann Chen, Nabil Saleh, Gregory D. Ayers, Chi Yan, Ann Richmond, et al.
Inhibition of autocrine HGF maturation overcomes cetuximab resistance in colorectal cancer. Cell Mol Life Sci. 2024 Jan 12;81(1):28. Vivian Truong Jones Ramona Graves-Deal, Gregory D Ayers, Qi Liu, Robert J Coffey, Bhuminder Singh, et al.
From goal to outcome: Analyzing the progression of biomedical sciences PhD careers in a longitudinal study using an expanded taxonomy. FASEB Bio advances. Volume 5, Issue 11, November 2023.Pages 427-452. Chalkley R, Gould K, et al.
Tumor therapy by targeting extracellular hydroxyapatite using novel drugs: A paradigm shift. Cancer Med. 024 Jan 18. Oliver McIntyre, Fiona Yull, Julie Rhoades, Lisa McCawley, Barbara Fingleton, et al.
Clinical Pathogenesis, Molecular Mechanisms of Gastric Cancer Development. Curr Top Microbiol Immunol. 2023;444:25-52. Wroblewski LE, Peek RM Jr.