New Publications

Approximating Projections of Conformational Boltzmann Distributions with AlphaFold2 Predictions: Opportunities and Limitations. Brown BP, Stein RA, Meiler J, Mchaourab HS. J Chem Theory Comput. 2024 Jan 12. doi: 10.1021/acs.jctc.3c01081. Online ahead of print. Protein thermodynamics is intimately… Read More

Developing and evaluating pediatric phecodes (Peds-Phecodes) for high-throughput phenotyping using electronic health records. Grabowska ME, Van Driest SL, Robinson JR, Patrick AE, Guardo C, Gangireddy S, Ong HH, Feng Q, Carroll R, Kannankeril PJ, Wei WQ. J Am Med… Read More

Glucagon-like peptide-1 receptor activation stimulates PKA-mediated phosphorylation of raptor and this contributes to the weight loss effect of liraglutide. Le TDV, Liu D, Besing GK, Raghavan R, Ellis BJ, Ceddia RP, Collins S, Ayala JE. Elife. 2023 Nov 6;12:e80944. Read More

The interictal suppression hypothesis in focal epilepsy: network-level supporting evidence. Johnson GW, Doss DJ, Morgan VL, Paulo DL, Cai LY, Shless JS, Negi AS, Gummadavelli A, Kang H, Reddy SB, Naftel RP, Bick SK, Roberson SW, Dawant BM,… Read More

Prevalence, Risk Factors, and Sequelae of Asymptomatic Clostridioides difficile Colonization in Children with Cystic Fibrosis. Reasoner SA, Fazili IF, Bernard R, Parnell JM, Sokolow AG, Thomsen KF, Edwards KM, Brown RF, Nicholson MR. J Cyst Fibros. 2022… Read More

Correlated depressive symptoms within seroconcordant, expectant partners living with HIV in Zambézia Province, Mozambique: a cross-sectional study. Sack DE, Matino A, Graves E, Emilio A, Shepherd BE, De Schacht C, Audet CM. AIDS Care. 2022 Dec 6:1-9. doi: 10.1080/09540121.2022.2151558. Read More

T cells specific for α-myosin drive immunotherapy-related myocarditis. Axelrod ML, Meijers WC, Screever EM, Qin J, Carroll MG, Sun X, Tannous E, Zhang Y, Sugiura A, Taylor BC, Hanna A, Zhang S, Amancherla K, Tai W, Wright JJ, Wei SC,… Read More

Single-Cell Identification of Melanoma Biomarkers in Circulating Tumor Cells Fankhauser R, Chang M, Garrison Z, Berryman R, Lucero OM, Fuiten A, DePatie N, Seifert H, Kulkarni RP. Cancers. 2022; 14(19):4921. https://doi.org/10.3390/cancers14194921 The current standard for investigating tumors is surgical biopsy,… Read More

Impaired Dynamic Sarcoplasmic Reticulum Ca Buffering in Autosomal Dominant CPVT2. Wleklinski MJ, Kryshtal DO, Kim K, Parikh SS, Blackwell DJ, Marty I, Iyer VR, Knollmann BC. Circ Res. 2022 Sep 14:101161CIRCRESAHA121320661. doi: 10.1161/CIRCRESAHA.121.320661. Online ahead of print. Background:… Read More

Uropathogenic Escherichia coli subverts mitochondrial metabolism to enable intracellular bacterial pathogenesis in urinary tract infection. Beebout CJ, Robertson GL, Reinfeld BI, Blee AM, Morales GH, Brannon JR, Chazin WJ, Rathmell WK, Rathmell JC, Gama V, Hadjifrangiskou M. Read More