VUSM Research

MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors. Brown RE, Jacobse J, Anant SA, Blunt KM, Chen B, Vega PN, Jones CT, Pilat JM, Revetta F, Gorby AH, Stengel KR, Choksi YA, Palin K, Piazuelo MB, Washington… Read More

Emergency Medicine and Trauma Surgery researchers at Vanderbilt University Medical Center are joining Vanderbilt LifeFlight in a Department of Defense (DOD)-funded clinical trial aimed at improving survival with resuscitation techniques used to keep patients alive after a traumatic injury. Emergency medicine services (EMS) personnel currently use one of two common strategies… Read More

MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors. Brown RE, Jacobse J, Anant SA, Blunt KM, Chen B, Vega PN, Jones CT, Pilat JM, Revetta F, Gorby AH, Stengel KR, Choksi YA, Palin K, Piazuelo… Read More

MD Class of 2022 Photo: Anne Rayner Each spring, Vanderbilt University School of Medicine recognizes members of the graduating MD class for outstanding academic achievement, service, research, and leadership. VUSM faculty and fellow students celebrated the following recipients of school and departmental awards at the MD Class Day ceremony on… Read More

Temporal lobe epilepsy lateralisation and surgical outcome prediction using diffusion imaging. Johnson GW, Cai LY, Narasimhan S, González HFJ, Wills KE, Morgan VL, Englot DJ. J Neurol Neurosurg Psychiatry. 2022 Mar 28:jnnp-2021-328185. doi: 10.1136/jnnp-2021-328185. Online… Read More

Introduction to the BioChemical Library (BCL): An Application-Based Open-Source Toolkit for Integrated Cheminformatics and Machine Learning in Computer-Aided Drug Discovery. Brown BP, Vu O, Geanes AR, Kothiwale S, Butkiewicz M, Lowe EW Jr, Mueller R, Pape R, Mendenhall J, Meiler J. Read More

Integrating gene expression and clinical data to identify drug repurposing candidates for hyperlipidemia and hypertension. Wu P, Feng Q, Kerchberger VE, Nelson SD, Chen Q, Li B, Edwards TL, Cox NJ, Phillips EJ, Stein CM, Roden DM, Denny JC, Wei WQ. Read More

Digital health interventions — delivered via technologies including text messages, apps and websites — are increasingly common for supporting chronic disease self-care. Although studies have focused on improving patient engagement with these interventions, limited research has addressed the association between engagement and clinical outcomes.  Lyndsay Nelson, PhD, Andrew Spieker, PhD, and… Read More

HDAC inhibitors stimulate LIFR when it is repressed by hypoxia or PTHrP in breast cancer. Edwards CM, Clements ME, Vecchi LA 3rd, Johnson JA, Johnson RW. J Bone Oncol. 2021 Dec 1;31:100407. doi: 10.1016/j.jbo.2021.100407. eCollection 2021 Dec. Breast cancer… Read More

by Lexie Little When William Quach (MD ’23) arrived at Vanderbilt University School of Medicine after studying biology at the University of California San Diego, he brought research experience with him. Quach, an aspiring anesthesiologist, examined how a specific protein traditionally known to play a role in the death… Read More