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MariaSanta Mangione (Gould Lab) was recently awarded an NIH/NIGMS grant for "Investigating the Regulation and Structural Features of the conserved Membrane-Binding F-BAR Protein Cdc15." Her current research is centered on the F-BAR protein Cdc15, and the formation of the cytokinetic ring.   … Read More

Research assistant professor, Jeff Franklin, and other investigators at Vanderbilt University Medical Center, have published research regarding an important feature of colorectal cancer (CRC) that could eventually lead to the development of non-invasive means of monitoring cancer progression. The team’s research, published in eLIFE, indicates that colorectal cancer cells release tiny RNAs called… Read More

Meredith Weck, a graduate student in Matt Tyska's Lab, was recently award an NIH/NIDDK grant for "Investigating the Role of Myosin 7b in Intra-Microvillar Transport."… Read More

Associate Professor and PI, Ken Lau, recently landed an NIH/NIDDK grant for research in  "Spatio-temporal Dissection of Epithelial Cell Hierarchies in Gut Inflammation."… Read More

Matthew Tyska, Ph.D., and colleagues previously discovered that the brush border’s densely packed microvilli – finger-like membrane protrusions – are connected to each other via cadherin adhesion molecules. Now, the investigators have demonstrated a critical role for a protein called ANKS4B in stabilizing the cadherin-based adhesions between microvilli to build… Read More

The NCI is asking for annual increases of 7 percent over the next decade. Congress increased funding for NCI by 5.25 percent for 2016. Vanderbilt-Ingram Cancer Center (VICC) researchers – Kathy Gould, Bill Tansey, and Ian Macara – explain what that funding means for their work. Read More

Andrea Page-McCaw was recently awarded a new R01 from the National Institute of General Medical Sciences (NIGMS): 1R01GM117899, 2/1/2016-12/31/2019, NIH/NIGMS, "Wnt/Wg Extracellular Ligand Distribution and Regulation."… Read More

Kathleen Gould, Melanie Ohi, and colleagues have found that certain proteins involved in cell division don’t function as previously thought. Instead of bending membranes into tubes, these “F-BAR” proteins — named for a domain they share — appear to form patches on the membrane where the cell’s internal actin cytoskeleton and… Read More

Irina Kaverina, associate professor of cell and developmental biology has been named to the 2016 class of Chancellor Faculty Fellows. The class comprises highly accomplished, recently tenured faculty from the humanities, social sciences, life and physical sciences, and clinical sciences, as well as business, education and engineering. "These extraordinary faculty members exemplify… Read More

Ken Lau, Ph.D., and colleagues have developed a method for preparing single-cell suspensions from epithelial tissues – the type of tissue from which many diseases arise. They describe the new method, DISSECT (Disaggregation for Intracellular Signaling in Single Epithelial Cells from Tissue), in the journal Molecular Systems Biology. Read More