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Thank you for visiting the internet home of the Chemical and Physical Biology (CPB) graduate program at Vanderbilt University. The CPB program fosters education and training at the interface of the chemical sciences, physical sciences, and biology. The course work and research components of the program prepare students for research careers in which they are able to bring state-of-the-art tools of the modern chemical and physical sciences, mathematics, engineering, and computing to bear on cutting-edge problems in biology and medicine. The CPB program was founded by Drs. Al Beth and Hassane Mchaourab in 2007.

The program encompasses four tracks: Chemical Biology, Structural Biology and Molecular Biophysics, Systems Biology, and Imaging Science. Each track has a curriculum of core classes that provide students with foundational knowledge in that discipline, as well as elective offerings that serve to tailor and customize each student’s curriculum.  Each track is directed by a senior member of the Vanderbilt faculty and is associated with one or more research centers and institutional training grants. To help you learn more about the CPB program, please explore the rest of our site and contact the program leadership with questions.


Bruce Damon, PhD

Program Director

Recent Publications and  Findings from Our Students

Chifman J, Arat S, Deng Z, Lemler E, Pino JC, Harris LA, Kochen MA, Lopez CF, Akman SA, Torti FM, Torti SV, Laubenbacher R. Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective. PLoS Computational Biology. 2017 Feb;13(2). e1005352

Simmons AJ, Scurrah CR, McKinley ET, Herring CA, Irish JM, Washington MK, Coffey RJ, Lau KS. Impaired coordination between signaling pathways is revealed in human colorectal cancer using single-cell mass cytometry of archival tissue blocks. 2016 Oct 11. PMID: 27729552

Poorman ME, Chaplin VL, Wilkens K, Dockery MD, Giorgio TD, Grissom WA, Caskey C. Erratum to: Open-source, small-animal magnetic resonance-guided focused ultrasound system. 2016 Oct 19. PMID: 27777767

Choby JE, Mike LA, Mashruwala AA, Dutter BF, Dunman PM, Sulikowski GA, Boyd JM, Skaar EP. A Small-Molecule Inhibitor of Iron-Sulfur Cluster Assembly Uncovers a Link between Virulence Regulation and Metabolism in Staphylococcus aureus. 2016 Oct 20. PMID: 27773628

Wu SY, Zou P, Fuller AW, Mishra S, Wang Z, Schey KL, Mchaourab HS. Expression of Cataract-linked γ-crystallin Variants in Zebrafish Reveals a Proteostasis Network that Senses Protein Stability. 2016 Oct 21. PMID: 27770023

Ostenson J, Pujara Ac, Mikheev A, Moy L, Kim SG, Melsaether AN, Jhaveri K, Adams S, Faul D, Glielmi C, Geppert C, Feiweier T, Jackson K, Cho GY, Boada FE, Sigmund EE. Voxelwise analysis of simultaneously acquired and spatially correlated 18 F-fluorodeoxyglucose (FDG)-PET and intravoxel incoherent motion metrics in breast cancer. 2016 Oct 25. PMID: 27779790

Mousa JJ, Sauer MF, Sevy AM, Finn JA, Bates JT, Alvarado G, King HG, Loerinc LB, Fong RH, Doranz BJ, Correia BE, Kalyuzhniy O, Wen X, Jardetzky TS, Schief WR, Ohi MD, Crowe JE JR. Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein. 2016 Nov 1.PMID: 27626297