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High Throughput Screening Facility

Publication Guidelines

As you near publishing work that used HTS resources, please consider the following:

Small Molecule Naming
When referring to Vanderbilt library small molecules and other registered compounds in presentations, we encourage you to use the full 7-digit VU#, e.g. VU0824980. This provides a unique reference and allows proper tracking.

Authorship
Some of the projects that we support require significant intellectual input from HTS research faculty and staff in a way to warrant co-authorship on publications and listing as co-PI on grants. Examples include contributing to the design and development of an assay and determining the approach for and carrying out data analysis.

We request that the recommendations for authorship of the International Committee of Medical Journal Editors (ICMJE) be followed and that the PI engages HTS collaborators during the project and manuscript preparation. According to the ICMJE recommendations, individuals who meet all of the following criteria should be included as co-authors:

· Substantial contributions to the conception or design of the work; or the acquisition,   analysis, or interpretation of data for the work; AND
· Drafting the work or revising it critically for important intellectual content; AND
· Final approval of the version to be published; AND
· Agreement to be accountable for all aspects of the work in ensuring that questions   related to the accuracy or integrity of any part of the work are appropriately
investigated and resolved.

Acknowledgements
Depending on the resource(s) that you use within HTS (including Compound Management and Informatics), a general or more specific acknowledgment may be appropriate. Below are examples of acknowledgements to include.

Resource Example Acknowledgement
HTS Instruments Experiments were performed in the Vanderbilt High-Throughput Screening (HTS) Core Facility with assistance provided by <staff member names>. The HTS Core receives support from the Vanderbilt Institute of Chemical Biology and the Vanderbilt Ingram Cancer Center (P30 CA68485).
Seahorse Analyzer* The Agilent Seahorse Extracellular Flux Analyzer is housed and managed within the Vanderbilt High-Throughput Screening Core Facility, an institutionally supported core, and was funded by NIH Shared Instrumentation Grant 1S10OD018015.
Panoptic 2* The WaveFront Biosciences Panoptic kinetic imaging plate reader is housed and managed within the Vanderbilt High-Throughput Screening Core Facility, an institutionally supported core, and was funded by NIH Shared Instrumentation Grant 1S10OD021734.
NIH Clinical Collections The NIH Clinical Collection is provided through the National Institutes of Health Molecular Libraries Roadmap Initiative and was distributed by the Vanderbilt High-throughput Screening Core Facility. The HTS Core receives support from the Vanderbilt Institute of Chemical Biology and the Vanderbilt Ingram Cancer Center (P30 CA68485).
SelleckChem FDA Approved The FDA approved library was provided by the Vanderbilt CTSA (UL1TR00044) and distributed by the Vanderbilt High-Throughput Screening Core Facility. The HTS Core receives support from the Vanderbilt Institute of Chemical Biology and the Vanderbilt Ingram Cancer Center (P30 CA68485).
SelleckChem Anti-cancer and Protein Kinase Inhibitor Collections The anti-cancer and protein kinase inhibitor collections were provided by funds donated by the Vanderbilt Ingram Cancer Center (P30 CA68485), the Vanderbilt Center for Cancer Targeted Therapies (part of the VICC), Dr. Lawrence J. Marnett, and Dr. Michael Savona.
Marnett Library The Marnett library was donated by Lawrence J. Marnett.
Other Libraries The <collection name> was distributed by the Vanderbilt High-Throughput Screening Core Facility. The HTS Core receives support from the Vanderbilt Institute of Chemical Biology and the Vanderbilt Ingram Cancer Center (P30 CA68485).

* NIH requires citation of S10 grant for instruments purchased using these funds. The Seahorse falls in this category.