Paula Hurley
Department of Medicine, Division of Hematology and Oncology
Program in Cancer Biology
The goal of our laboratory is to reduce the death and suffering caused by prostate cancer. Cancer localized to the prostate is often curable with treatments such as surgery or radiation therapy; however, once prostate cancer has spread beyond the prostate to other organs or to bone, it is an incurable disease. Our lab focuses on identifying both cancer cell-autonomous and non-cancer cell-autonomous genetic and molecular pathways that promote lethal prostate cancer and cause therapy resistance.
Keywords: prostate , cancer , metastasis , tumor microenvironment , mesenchymal stem cell , therapy resistance
Research Area: Cancer Biology , Cancer Immunology , Cell Cycle, DNA Repair, and Chromosome Biology , Cell Signaling , Gene Regulation , Genomics , Molecular Pathology