![](https://cdn.vanderbilt.edu/vu-web/medschool-wpcontent/sites/24/2018/08/25030913/Doyle-Michael-Patrick-Mike-IGP_photo.jpg)
Mike Doyle
Pennsylvania State University
James Crowe lab
I study the human antibody response to flavivirus infection. Using B-cells derived from human survivors of infection, I isolate monoclonal antibodies that display protective characteristics, namely neutralization of the virus of interest. These studies can result in new antibody-based therapeutics, and can also assist in guiding the rational design of novel vaccines.