Bih-Hwa Shieh
Department of Pharmacology
Neuroscience Graduate Program (NGP)
We study the regulation of rhodopsin endocytosis in Drosophila photoreceptors. We investigate the real-time trafficking using transgenic flies expressing GFP or mCherry tagged rhodopsin or arrestin. We believe that insights into light-regulated rhodopsin endocytosis will further better understanding of GPCR trafficking in vivo.
We study the regulation of rhodopsin endocytosis in Drosophila photoreceptors. We investigate the real-time trafficking using transgenic flies expressing GFP or mCherry tagged rhodopsin or arrestin. We believe that insights into light-regulated rhodopsin endocytosis will further better understanding of GPCR trafficking in vivo.
Keywords: endocytosis , GPCR , rhodopsin , trafficking , Genetics , Drosophila
Research Area: Cell Signaling , Visual Sciences , Developmental Neuroscience