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Carlos Detres Roman

University of Puerto Rico

Mary Philip lab

My research is currently focused on studying the differentiation of tumor-specific T cells in mice with either hematologic or solid tumors by assessing their immunophenotype and functional status and comparing how their transcriptional and chromatin landscapes evolve over time. By studying how T cells of the same specificity differentiate and function in different tumor microenvironments, we can identify features and signals of the tumor microenvironment that drive T cell dysfunction.