Claus Schneider
Vanderbilt Institute of Chemical Biology (VICB)
Vanderbilt-Ingram Cancer Center (VICC)
Vanderbilt Center for Mucosal Inflammation and Cancer (CMIC)
Department of Pharmacology
Department of Medicine
Division of Clinical Pharmacology
We study biotransformations of small molecules with relevance to human health and disease in vitro and in vivo. We determine the structures of novel metabolites (LC-MS, NMR), analyze enzymes and reaction mechanisms involved in their formation, and quantify their abundance in animals and humans. We investigate the biological activity of the newly identified metabolites using cell culture and animal models.
We study biotransformations of small molecules with relevance to human health and disease in vitro and in vivo. We determine the structures of novel metabolites (LC-MS, NMR), analyze enzymes and reaction mechanisms involved in their formation, and quantify their abundance in animals and humans. We investigate the biological activity of the newly identified metabolites using cell culture and animal models.
Keywords: bioactive lipids , inflammation , natural products , chemical synthesis , pharmacokinetics , alternative medicine
Research Area: Diabetes, Obesity, Metabolism , Chemical Biology