James Patton
RNA Journal Club
Extracellular Vesicle Interest Group
Vanderbilt Vision Research Center (VVRC)
Protein Trafficking Club
Stem and Progenitor Cell Interest Group
Epithelial Biology Center (EBC)
Cellular, Biochemical, and Molecular Sciences (CBMS) Training Program
The Patton lab is an RNA biology lab with projects that focus on retina regeneration and colon cancer. For retina regeneration, we use zebrafish as a model organism to study how an adult stem cell (Muller glia) can respond to injury to replace any lost cell type. For colon cancer, we are studying how cell-cell signaling can be mediated by extracellular vesicles that deliver proteins, RNAs, and lipids and are key to interactions in the tumor microenvironment and metastasis.
The Patton lab is an RNA biology lab with projects that focus on retina regeneration and colon cancer. For retina regeneration, we use zebrafish as a model organism to study how an adult stem cell (Muller glia) can respond to injury to replace any lost cell type. For colon cancer, we are studying how cell-cell signaling can be mediated by extracellular vesicles that deliver proteins, RNAs, and lipids and are key to interactions in the tumor microenvironment and metastasis.
Keywords: Regeneration , Cancer , RNA , Zebrafish , Exosomes , Retina
Research Area: Stem Cell Biology & Regeneration , RNA Biology , Cancer Biology , Cell Signaling , Visual Sciences , Developmental Biology