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Jeff Johnston

Department of Chemistry
Vanderbilt Institute of Chemical Biology (VICB)


We apply the principles and techniques of organic chemistry to create new reagents and reactions. These developments are driven by their potential to solve longstanding problems in small molecule and peptide synthesis. We collaborate with colleagues at Vanderbilt and elsewhere to advance our understanding of disease pathways using small molecule tools, ultimately aimed at early stage drug development.

We apply the principles and techniques of organic chemistry to create new reagents and reactions. These developments are driven by their potential to solve longstanding problems in small molecule and peptide synthesis. We collaborate with colleagues at Vanderbilt and elsewhere to advance our understanding of disease pathways using small molecule tools, ultimately aimed at early stage drug development.

Keywords: organic synthesis , catalysis , total chemical synthesis , medicinal chemistry , alkaloids , peptides

Research Area: Drug Design , Chemical Biology