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John York

Vanderbilt Center for Structural Biology (CSB)
Vanderbilt Genetics Institute (VGI)
Vanderbilt-Ingram Cancer Center (VICC)
Vanderbilt Institute of Chemical Biology (VICB)
Department of Biochemistry
Department of Pharmacology


The York laboratory studies the biology, biochemistry and enzyme regulation of cellular signal transduction pathways. We have discovered complex patterns of chemical codes that establish communication networks which ensure specific responses to developmental and adaptive queues required for life. Our multidisciplinary curiosity-driven approach has enabled trainees to make fundamental discoveries that have uncovered new areas of biology and helped elucidate the pathophysiology of disease.

The York laboratory studies the biology, biochemistry and enzyme regulation of cellular signal transduction pathways. We have discovered complex patterns of chemical codes that establish communication networks which ensure specific responses to developmental and adaptive queues required for life. Our multidisciplinary curiosity-driven approach has enabled trainees to make fundamental discoveries that have uncovered new areas of biology and helped elucidate the pathophysiology of disease.

Keywords: Disease , Mental Illness and Lithium , Metabolism , Signaling and Informatics , Protein Folding , Biochemistry

Research Area: Structural Biology , Diabetes, Obesity, Metabolism , Molecular Pathology , Cell Signaling