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Kara McNamara

University of Massachusetts

Keith Wilson Lab

I will be exploring the SMOX-driven dysregulation of polyamine metabolism and the associated generation of spermidine and hypusination and its connection to risk factors associated with gastric disease progression to carcinogenesis. Specifically, I will aim to analyze the role of SMOX in hypusination during H. pylori infection and determine the effect of hypusination in GECs on inflammation and carcinogenesis.