Keith Wilson
Vanderbilt Center for Mucosal Inflammation and Cancer (CMIC)
Vanderbilt Digestive Diseases Research Center (VDDRC)
Department of Medicine; Division of Gastroenterology, Hepatology and Nutrition
Department of Pathology, Microbiology and Immunology (PMI)
Program in Cancer Biology
Our laboratory investigates gastrointestinal mucosal immunology, inflammation, and carcinogenesis. We focus on two diseases, Helicobacter pylori infection of the stomach and the link to gastric cancer, and inflammatory bowel disease and the link to colon cancer. Through basic and translational studies, using many mutant mouse lines, human tissues, and a variety of techniques we aim to assess factors such as alterations in immunometabolism in disease that can serve as opportunities for disease prevention.
Keywords: macrophages , Helicobacter pylori , gastric cancer , colitis , polyamines , immunometabolism
Research Area: Bacteriology , Immunology , Cancer Biology , Cancer Immunology , Molecular Pathology