![](https://cdn.vanderbilt.edu/vu-web/medschool-wpcontent/sites/24/2018/08/25031120/MariaAgostini1_0.jpg)
Maria Agostini
University of Michigan
Mark Denison lab
My research focuses on identifying antivirals that inhibit Coronaviruses. Specifically, my project focuses on the nucleoside prodrug GS-5734. The goal of the project is to better understand the mechanisms of inhibition and resistance to this nucleoside in Coronaviruses, especially in the context of the Coronavirus RNA proofreading activity.