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Matthew Dungan

College of William and Mary

Amanda Doran lab

My project focuses on understanding the mechanisms of innate immune system dysregulation that leads to atherosclerosis, the leading cause of cardiovascular disease. Specifically, I study PirB, a mouse ortholog of a human immunomodulatory receptor family. I am interested in PirB’s role in perpetuating the unresolved innate immune response observed in arterial plaques.