Pierre Massion
Early Detection Research Network NCI
Vanderbilt Medical-image Analysis and Statistical Interpretation lab (MASI)
Vanderbilt-Ingram Cancer Center (VICC)
Researchers in the laboratory investigate the molecular determinants of risk for lung cancer development and the determinants of different tumor behavior (indolent vs aggressive). We study how metabolic reprogramming of the airway epithelium sets the stage for the development of genomic instability. Ultimately our research aims at answering key clinical questions such as who is at high risk for lung ca or how the immune system prevents most airway epithelial cells that undergo malignant in check.
Researchers in the laboratory investigate the molecular determinants of risk for lung cancer development and the determinants of different tumor behavior (indolent vs aggressive). We study how metabolic reprogramming of the airway epithelium sets the stage for the development of genomic instability. Ultimately our research aims at answering key clinical questions such as who is at high risk for lung ca or how the immune system prevents most airway epithelial cells that undergo malignant in check.
Keywords: Epithelial cancer biology , Metabolic reprogramming , Genomic instability , Immunoprevention , personalized risk assessment , Early detection
Research Area: Epithelial Biology , Cell Cycle, DNA Repair, and Chromosome Biology , Immunology , Cancer Biology , Cancer Immunology , Molecular Pathology