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Shannon Townsend

Amherst College

Maureen Gannon lab

It has been shown that connective tissue growth factor has promoted the insulin-producing beta cell's proliferation. As of right now, there is no receptor known for which CTGF binds to but a thought is that it might bind to integrins. Therefore, my project is to define whether integrins may be its receptor or possibly something else. Finally, I hope to elucidate the upstream and downstream mechanisms by which CTGF causes this proliferation.