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Vera Mayhew

Brigham Young University

Rachelle Johnson lab

Breast Cancer cells commonly metastasize to bone where they can stay dormant for years. We have found that when cells lose the expression of the leukemia inhibitory factor receptor (LIFR), they exit dormancy and begin to grow into metastatic lesions. My project looks at identifying downstream targets of LIFR and characterizing their role in cellular reactivation.