Archive

The new grant (1R01DK115620-01), titled DESIGNING SELECTIVE TALK-1 INHIBITORS TO REDUCE BETA-CELL DYSFUNCTION IN DIABETES, will test the central hypothesis that the inhibition of TALK-1 potassium channels in pancreatic beta cells normalizes Ca2+ homeostasis under diabetic conditions, preventing beta-cell dysfunction and maintaining euglycemia. Read More

Work from the Cherrington/Moore labs published in Diabetes……… Read More

JCI publishes Ian Williams paper….. Insulin exits skeletal muscle capillaries by fluid-phase transport… Read More

Reid Bolus published a first author paper in Molecular Metabolism Elevating adipose eosinophils in obese mice to physiologically normal levels does not rescue metabolic impairments… Read More

Molecular metabolism publishes a paper by Nick Vierra….. TALK-1 reduces delta-cell endoplasmic reticulum and cytoplasmic calcium levels limiting somatostatin secretion  … Read More

Daniel Lark publishes in Diabetes…. Reduced Nonexercise Activity Attenuates Negative Energy Balance in Mice Engaged in Voluntary Exercise  … Read More

Marcela Brissova, Rachana Haliyur and Diane Saunders are co-first authors of a paper in Cell Reports……. α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes  … Read More

Paper in Biological Psychiatry by Brian Shonesy….. Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior… Read More

Magnuson lab publishes in Diabetes….. Chronic β-Cell Depolarization Impairs β-Cell Identity by Disrupting a Network of Ca2+-Regulated Genes… Read More

Diabetes publishes work from Jason Spaeth…… Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning… Read More