MP&B 8333: Molecular Aspects of Obesity and Diabetes
Course Description:
This course (2 credit hours) is designed to introduce first-year IGP students to some of the major areas of interest in the fields of obesity and diabetes research. In the first part of the course the lecturers will discuss the characteristics of diabetes and obesity in terms of whole-body metabolism. The use of mouse models, a major tool to study metabolism, will be emphasized. The second part of the course will focus on the insulin-producing cells of the pancreas: how they develop, how insulin secretion is regulated, and how insulin gene transcription is controlled. The third part of the course will focus on the mechanism of insulin action at the molecular level. The final part of the course will focus on the regulation of lipid metabolism and the latest theories on the molecular causes of insulin resistance and obesity. The NIH-funded Molecular Endocrinology Training Program (METP) provides support for eight IGP students in the second and third years of their graduate studies. The METP strongly encourages students who wish to be considered for METP funding take this Spring Elective.
COURSE SCHEDULE: SPRING 2017
Time: MWF, 1-3pm
Location: 736 RRB
Credit: 2 hours
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Wednesday, Jan. 4th |
Richard O'Brien Course Introduction |
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Friday, Jan. 6th |
Owen McGuinness; Flextime: Thomas Beck Regulation of Blood Sugar Levels at the Whole Animal Level |
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Monday, Jan. 9th |
Dave Wasserman; Flextime: Elijah Trefts Hormonal Regulation of Muscle Glucose Uptake at the Whole Animal Level |
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Wednesday, Jan. 11th |
Dale Edgerton; Flextime: Guillaume Kraft Hormonal Regulation of Liver Glucose Production at the Whole Animal Level |
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Friday, Jan. 13th |
Richard O'Brien; Flextime: Karin Bosma The Mechanisms of Glucocorticoid, Glucagon and Insulin Action |
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Monday, Jan. 16th |
Martin Luther King Day. No Class. |
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Wednesday, Jan. 18th |
Ray Blind; Flextime: Corey Seacrist New Drug Design Paradigms for Regulating Nuclear Receptors in the Liver |
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Friday, Jan. 20th |
David Jacobson; Flextime: Nick Vierra Regulation of Insulin Secretion |
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Monday, Jan. 23rd |
Danielle Dean; Flextime: Rachana Haliyur Regulation of Glucagon Secretion |
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Wednesday, Jan. 25th |
Maureen Gannon; Flextime: Peter Kropp Development of the Endocrine Pancreas |
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Friday, Jan. 27th |
Al Powers; Flextime: Neil Phillips Regulation of Insulin Secretion |
| Monday, Jan. 30 |
John Stafford; Flextime: Josh Neuman Triglycerides, an Under-Appreciated Risk Factor for Cardiovascular Disease in Obesity and Diabetes. |
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Wednesday, Feb. 1st |
Alyssa Hasty; Flextime: Arion Kennedy Metabolic Impact of Adipose Tissue |
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Friday, Feb. 3rd |
Kasey Vickers; Flextime: Leslie Roteta Intercellular Communication in Diabetes |
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Monday, Feb. 6th |
Mark Magnuson; Flextime: Karrie Dudek Making New Beta Cells: Strategies and Challenges |
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Wednesday, Feb. 8th |
Kevin Niswender; Flextime: Kevin Niswender Introduction to Energy Homeostasis; Endocrine Feedback Loops |
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Friday, Feb. 10th |
Danny Winder; Flextime: Nick Harris Introduction to CNS Control of Feeding Behavior and Metabolism |
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Monday, Feb. 13th |
End of course exam |