AMPA receptors (AMPARs) are ligand-gated cation channels whose appropriate activity and regulation are integral to most central nervous system function. They mediate the majority of excitatory neurotransmission and their dysregulation has been implicated in many cognitive disorders. My research focuses on the molecular details of auxiliary subunit interactions with the AMPAR. Using biochemical and structural biology techniques, we hope to illuminate the molecular basis of interaction between these two proteins and how that relates to the auxiliary subunit’s modulation of AMPAR in vivo.
Graduate Student, Terunaga Nakagawa lab, Molecular Physiology and Biophysics
766 RRB (MRB I)