Imaging Science, Magnetic Resonance Imaging (MRI)
Dr. Gore's research program is focused on the development and application of imaging, especially magnetic resonance imaging and spectroscopy techniques, in clinical and basic science. Imaging of human subjects and small animals provides unique information on tissue structure and function, and is being applied in a variety of different applications in neuroscience, cancer research and studies of metabolism. A general theme of interest is to understand the physical and physiological factors that affect MRI signals and to use this knowledge to devise non-invasive imaging methods that provide new types of information as well as for developing new applications of imaging. A second major theme is the development of methods for studying human brain structure and function using MRI and for integrating fMRI data with other imaging methods such as NIR and EEG. Applications of structural and functional MRI to the brain are performed in collaboration with investigators from psychology, psychiatry and other departments. A third major theme is the use of multi-modality imaging (MRI, PET, CT, optical and ultrasound) to study small animals, including mouse models of human cancer and other genetically modified mice. Many projects also involve the development and application of advanced image analysis methods and computer algorithms.