Our lab studies the function of potassium channels in electrically excitable endocrine cells within the pancreas. We are particularly interested in the β-cell specific potassium channel, TALK-1. TALK-1 is the most abundant potassium channel in the β-cell, and a polymorphism within TALK-1 has been associated with an increased risk for Type-2 diabetes. Our lab has previously shown that TALK-1 channels regulate the β-cells ability to release insulin in response to glucose. My work focuses on characterizing this regulation so that we can better understand the function that the channel plays in diabetes.
Graduate Student, Jacobson laboratory, Molecular Physiology & Biophysics