New Publications
MSTPublications: October 2022
Oct. 31, 2022—Single-Cell Identification of Melanoma Biomarkers in Circulating Tumor Cells Fankhauser R, Chang M, Garrison Z, Berryman R, Lucero OM, Fuiten A, DePatie N, Seifert H, Kulkarni RP. Cancers. 2022; 14(19):4921. https://doi.org/10.3390/cancers14194921 The current standard for investigating tumors is surgical biopsy, which is costly, invasive, and difficult to perform serially. As an adjunct, circulating tumor cells...
MSTPublications: September 2022
Sep. 28, 2022—Impaired Dynamic Sarcoplasmic Reticulum Ca Buffering in Autosomal Dominant CPVT2. Wleklinski MJ, Kryshtal DO, Kim K, Parikh SS, Blackwell DJ, Marty I, Iyer VR, Knollmann BC. Circ Res. 2022 Sep 14:101161CIRCRESAHA121320661. doi: 10.1161/CIRCRESAHA.121.320661. Online ahead of print. Background: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a potentially lethal cardiac arrhythmia syndrome triggered by catecholamines released during...
MSTPublications: August 2022
Aug. 30, 2022—Uropathogenic Escherichia coli subverts mitochondrial metabolism to enable intracellular bacterial pathogenesis in urinary tract infection. Beebout CJ, Robertson GL, Reinfeld BI, Blee AM, Morales GH, Brannon JR, Chazin WJ, Rathmell WK, Rathmell JC, Gama V, Hadjifrangiskou M. Nat Microbiol. 2022 Sep;7(9):1348-1360. doi: 10.1038/s41564-022-01205-w. Epub 2022 Aug 22. Urinary tract infections are among the most common...
MSTPublications: July 2022
Jul. 29, 2022—Allele-specific activation, enzyme kinetics, and inhibitor sensitivities of EGFR exon 19 deletion mutations in lung cancer. Brown BP, Zhang YK, Kim S, Finneran P, Yan Y, Du Z, Kim J, Hartzler AL, LeNoue-Newton ML, Smith AW, Meiler J, Lovly CM. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2206588119. doi: 10.1073/pnas.2206588119. Epub 2022 Jul...
MSTPublications: June 2022
Jun. 29, 2022—MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors. Brown RE, Jacobse J, Anant SA, Blunt KM, Chen B, Vega PN, Jones CT, Pilat JM, Revetta F, Gorby AH, Stengel KR, Choksi YA, Palin K, Piazuelo MB, Washington MK, Lau KS, Goettel JA, Hiebert SW, Short SP, Williams CS. JCI Insight....
MSTPublications: May 2022
May. 31, 2022—MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors. Brown RE, Jacobse J, Anant SA, Blunt KM, Chen B, Vega PN, Jones CT, Pilat JM, Revetta F, Gorby AH, Stengel KR, Choksi YA, Palin K, Piazuelo MB, Washington MK, Lau KS, Goettel JA, Hiebert SW, Short SP, Williams CS. JCI...
MSTPublications: April 2022
Apr. 28, 2022—Temporal lobe epilepsy lateralisation and surgical outcome prediction using diffusion imaging. Johnson GW, Cai LY, Narasimhan S, González HFJ, Wills KE, Morgan VL, Englot DJ. J Neurol Neurosurg Psychiatry. 2022 Mar 28:jnnp-2021-328185. doi: 10.1136/jnnp-2021-328185. Online ahead of print. Objective: We sought to augment the presurgical workup of medically refractory temporal lobe epilepsy by creating a...
MSTPublications: March 2022
Apr. 4, 2022—Introduction to the BioChemical Library (BCL): An Application-Based Open-Source Toolkit for Integrated Cheminformatics and Machine Learning in Computer-Aided Drug Discovery. Brown BP, Vu O, Geanes AR, Kothiwale S, Butkiewicz M, Lowe EW Jr, Mueller R, Pape R, Mendenhall J, Meiler J. Front Pharmacol. 2022 Feb 21;13:833099. doi: 10.3389/fphar.2022.833099. eCollection 2022. The BioChemical Library (BCL) cheminformatics...
MSTPublications: February 2022
Feb. 25, 2022—Integrating gene expression and clinical data to identify drug repurposing candidates for hyperlipidemia and hypertension. Wu P, Feng Q, Kerchberger VE, Nelson SD, Chen Q, Li B, Edwards TL, Cox NJ, Phillips EJ, Stein CM, Roden DM, Denny JC, Wei WQ. Nat Commun. 2022 Jan 10;13(1):46. doi: 10.1038/s41467-021-27751-1. Discovering novel uses for existing drugs, through...
MSTPublications: January 2022
Jan. 29, 2022—HDAC inhibitors stimulate LIFR when it is repressed by hypoxia or PTHrP in breast cancer. Edwards CM, Clements ME, Vecchi LA 3rd, Johnson JA, Johnson RW. J Bone Oncol. 2021 Dec 1;31:100407. doi: 10.1016/j.jbo.2021.100407. eCollection 2021 Dec. Breast cancer cells frequently disseminate to the bone marrow, where they either induce osteolysis or enter a dormant...