Elaine Shelton, Ph.D.

Assistant Professor of Pediatrics

: elaine.l.shelton@vanderbilt.edu

Selected Publications

Reese J, Shelton EL, Slaughter JC, McNamara PJ. Prophylactic Indomethacin Revisited [editorial]. J. Pediatr [print-electronic]. 2017 Jul; 186: 11-14.e1. PMID: 28396028, PMCID: PMC5520627, PII: S0022-3476(17)30385-2, DOI: 10.1016/j.jpeds.2017.03.036, ISSN: 1097-6833.
Hooper CW, Delaney C, Streeter T, Yarboro MT, Poole S, Brown N, Slaughter JC, Cotton RB, Reese J, Shelton EL. Selective serotonin reuptake inhibitor exposure constricts the mouse ductus arteriosus in utero. Am. J. Physiol. Heart Circ. Physiol [print-electronic]. 2016 Sep 9/1/2016; 311(3): H572-81. PMID: 27371685, PMCID: PMC5142184, PII: ajpheart.00822.2015, DOI: 10.1152/ajpheart.00822.2015, ISSN: 1522-1539.
Waleh N, Barrette AM, Dagle JM, Momany A, Jin C, Hills NK, Shelton EL, Reese J, Clyman RI. Effects of Advancing Gestation and Non-Caucasian Race on Ductus Arteriosus Gene Expression. J. Pediatr [print-electronic]. 2015 Nov; 167(5): 1033-1041.e2. PMID: 26265282, PMCID: PMC4661123, PII: S0022-3476(15)00733-7, DOI: 10.1016/j.jpeds.2015.07.011, ISSN: 1097-6833.
Herington JL, Swale DR, Brown N, Shelton EL, Choi H, Williams CH, Hong CC, Paria BC, Denton JS, Reese J. High-Throughput Screening of Myometrial Calcium-Mobilization to Identify Modulators of Uterine Contractility. PLoS ONE. 2015; 10(11): e0143243. PMID: 26600013, PMCID: PMC4658040, PII: PONE-D-15-12311, DOI: 10.1371/journal.pone.0143243, ISSN: 1932-6203.
El-Khuffash A, Jain A, Corcoran D, Shah PS, Hooper CW, Brown N, Poole SD, Shelton EL, Milne GL, Reese J, McNamara PJ. Efficacy of paracetamol on patent ductus arteriosus closure may be dose dependent: evidence from human and murine studies. Pediatr. Res [print-electronic]. 2014 Sep; 76(3): 238-44. PMID: 24941212, PMCID: PMC4321957, PII: pr201482, DOI: 10.1038/pr.2014.82, ISSN: 1530-0447.
Vucovich MM, Cotton RB, Shelton EL, Goettel JA, Ehinger NJ, Poole SD, Brown N, Wynn JL, Paria BC, Slaughter JC, Clark RH, Rojas MA, Reese J. Aminoglycoside-mediated relaxation of the ductus arteriosus in sepsis-associated PDA. Am. J. Physiol. Heart Circ. Physiol [print-electronic]. 2014 Sep 9/1/2014; 307(5): H732-40. PMID: 24993047, PMCID: PMC4187398, PII: ajpheart.00838.2013, DOI: 10.1152/ajpheart.00838.2013, ISSN: 1522-1539.
Shelton EL, Ector G, Galindo CL, Hooper CW, Brown N, Wilkerson I, Pfaltzgraff ER, Paria BC, Cotton RB, Stoller JZ, Reese J. Transcriptional profiling reveals ductus arteriosus-specific genes that regulate vascular tone. Physiol. Genomics [print-electronic]. 2014 Jul 7/1/2014; 46(13): 457-66. PMID: 24790087, PMCID: PMC4080279, PII: physiolgenomics.00171.2013, DOI: 10.1152/physiolgenomics.00171.2013, ISSN: 1531-2267.
Pfaltzgraff ER, Shelton EL, Galindo CL, Nelms BL, Hooper CW, Poole SD, Labosky PA, Bader DM, Reese J. Embryonic domains of the aorta derived from diverse origins exhibit distinct properties that converge into a common phenotype in the adult. J. Mol. Cell. Cardiol [print-electronic]. 2014 Apr; 69: 88-96. PMID: 24508561, PMCID: PMC4034360, PII: S0022-2828(14)00036-4, DOI: 10.1016/j.yjmcc.2014.01.016, ISSN: 1095-8584.
Shelton EL, Poole SD, Reese J, Bader DM. Omental grafting: a cell-based therapy for blood vessel repair. J Tissue Eng Regen Med [print-electronic]. 2013 Jun; 7(6): 421-33. PMID: 22318999, PMCID: PMC3672266, DOI: 10.1002/term.528, ISSN: 1932-7005.
Cotton RB, Shah LP, Poole SD, Ehinger NJ, Brown N, Shelton EL, Slaughter JC, Baldwin HS, Paria BC, Reese J. Cimetidine-associated patent ductus arteriosus is mediated via a cytochrome P450 mechanism independent of H2 receptor antagonism. J. Mol. Cell. Cardiol [print-electronic]. 2013 Jun; 59: 86-94. PMID: 23454087, PMCID: PMC3646934, PII: S0022-2828(13)00067-9, DOI: 10.1016/j.yjmcc.2013.02.010, ISSN: 1095-8584.
Shelton EL, Galindo CL, Williams CH, Pfaltzgraff E, Hong CC, Bader DM. Autotaxin signaling governs phenotypic heterogeneity in visceral and parietal mesothelia. PLoS ONE [electronic-print]. 2013; 8(7): e69712. PMID: 23936085, PMCID: PMC3723636, PII: PONE-D-13-15224, DOI: 10.1371/journal.pone.0069712, ISSN: 1932-6203.
Shelton EL, Bader DM. Thymosin ß4 mobilizes mesothelial cells for blood vessel repair. Ann. N. Y. Acad. Sci. 2012 Oct; 1269: 125-30. PMID: 23045980, PMCID: PMC3693742, DOI: 10.1111/j.1749-6632.2012.06713.x, ISSN: 1749-6632.