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Chair’s Message

Ege T. Kavalali, Ph.D.


Ege T. Kavalali, Ph.D.
Professor & Acting Chair, Department of Pharmacology
William Stokes Chair In Experimental Therapeutics



I am honored to welcome you to the Department of Pharmacology at Vanderbilt. We are one of the most distinguished Pharmacology departments in the country and one that has incredible potential to advance basic science and contribute to urgently-needed drug development in the coming years.

Our research interests include five major areas:

  • signal transduction
  • neuroscience
  • bioactive lipid metabolism
  • genetic basis of cardiovascular dysfunction
  • drug metabolism

Molecules under investigation include G-protein coupled receptors (rhodopsin, adrenergic, serotonin and receptors), heterotrimeric G-proteins, ion channels, transporters and regulatory proteins such as arrestins, protein kinases and protein phosphatases.  We provide training focused on critical thinking to promote innovation, scholarship and integrity.  To this end, we foster creativity, collegiality, and leadership.

Pharmacology in the News

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New faculty Rick Sando: A better understanding of brain circuitry

MyVU is spotlighting a select group of new faculty for 2020-21. Read more profiles in the series. By Lorena Infante Lara Our bra...

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Cohen Fund bolsters Siciliano’s memory research

  by Bill Snyder Cody Siciliano, PhD, assistant professor of Pharmacology in the Vanderbilt University School of Medi...

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New clue to Alzheimer’s disease

by Bill Snyder Reduced expression of Dlgap2, a gene important in signaling across the synapse between nerve cells, is associa...

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Assembling cell power plant machinery

by Leigh MacMillan Mitochondrial complex II is a four-subunit protein machine located in the mitochondrial membrane that link...

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‘Scavenger’ molecule may point to new atherosclerosis treatment

From left, Huan Tao, MD, PhD, Sean Davies, PhD, Jiansheng Huang, PhD, and MacRae Linton, MD, led the study that identified a pot...

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A potential new targeted therapy for metastatic melanoma

By Wendy Bindeman Melanoma is the most common of all cancers. The American Cancer Society estimates that over 100,000 new melan...

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Siciliano wins Fay/Frank Seed Grant and Alkermes Pathways Research Award

By Jenna Somers Cody Siciliano (Vanderbilt University) Assistant Professor of Pharmacology Cody Siciliano has been awarded the F...

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New tools to study bioactive lipids

by Leigh MacMillan NAEs are bioactive lipid molecules that appear to play roles in energy balance, inflammation, stress respo...

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Single mutation causes seizure disorder

by Leigh MacMillan Lennox-Gastaut syndrome is a severe early-onset seizure disorder that includes cognitive and behavioral ab...

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Robotic technology speeds arrhythmia gene classification

  by Leigh MacMillan Vanderbilt University Medical Center investigators have used high-throughput robotic technology ...

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Blocking stress-induced relapse

by Bill Snyder Stress is a precipitating factor for craving and relapse in cocaine use disorder. A part of the brain known as...

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A new contributor to atherosclerosis

by Leigh MacMillan Free radicals produced during oxidative stress react with membrane fatty acids to yield highly reactive li...