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News/Discoveries

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Blocking stress-induced relapse

by Bill Snyder Stress is a precipitating factor for craving and relapse in cocaine use disorder. A part of the brain known as...


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A new contributor to atherosclerosis

by Leigh MacMillan Free radicals produced during oxidative stress react with membrane fatty acids to yield highly reactive li...


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Kavalali receives Humboldt Research Award

Ege T. Kavalali, PhD, professor and acting chair of the Department of Pharmacology in the Vanderbilt University School of Medici...


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Cell fate signaling

by Leigh MacMillan The protein kinase MELK is thought to affect cell cycle regulation, proliferation and mitosis. Overexpress...


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Study explores potential new class of antidepressants

Max Joffe, PhD, left, P. Jeffrey Conn, PhD, and colleagues are studying a new class of antidepressants that may relieve symptoms...


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Team discovers one more piece to the autism puzzle

by Bill Snyder Mutations in a subunit of a receptor that binds the major inhibitory neurotransmitter GABAA in the brain have ...


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Guengerich, Sanders-Bush named ASPET fellows

  by Bill Snyder Vanderbilt University’s F. Peter (Fred) Guengerich, PhD, and Elaine Sanders-Bush, PhD, are among 22 ...


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A probiotic treatment for obesity?

by Leigh MacMillan Alterations in the gut microbiota — the microorganisms residing in the gastrointestinal tract — have been ...


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Defective transporter linked to autism

by Bill Snyder Signaling by the neurotransmitter dopamine is a critical regulator of movement, attention and reward. Disrupte...


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Potassium balance and glaucoma

by Sanjay Mishra Retinal ganglion cells (RGCs) make up the optic nerve. When RGCs degenerate due to elevated intraocular pres...


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Yohn named Postdoc of the Year at annual symposium; Sappington named Mentor of the Year

By Irene McKirgan Samantha Yohn, 2019 Vanderbilt Postdoc of the Year. (Anne Rayner/Vanderbilt) Postdoctoral scholar Samantha Yoh...


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The arrestin-GPCR connection

G-protein coupled receptors (GPCRs) are the “inbox” of environmental messages in mammalian cells. Because of their central role ...