Mabel Seto

Mabel Seto

Graduate Student, Lindsley laboratory

BSLAS, University of Illinois @ Urbana (2015)


The Lindsley laboratory focuses on drug discovery with an emphasis on the development of allosteric modulators for the validation and investigation of novel targets and mechanisms for a variety of different diseases. My project is on the development of novel and selective positive allosteric modulators for the metabotropic glutamate receptor subtype 7 (mGlu7). My primary goals are the chemical synthesis and optimization of the modulator as well as the exploration of the role of mGlu7 in the neurological disorder, schizophrenia. These studies may not only lead to a better understanding of the biology of mGlu7 in schizophrenia, but also in other neurological disorders.