2024 VICB Seminars
2024 Seminar Schedule
January 4: Doug Mitchell, University of Illinois at Urbana-Champaign, “Genomics-Enabled Discovery of New Molecules and Enzymes”
January 10: Peter Scott, University of Michigan, “We are Explorers in Radiochemical Space: Adventures in PET Imaging, Artificial Intelligence and Theranostics”
January 24: Matt Hall, NIH/National Center for Advancing Translational Sciences (NCATS), “Assays to Lead the Way: Drug Discovery at NCATS”
January 31: James Imlay, University of Illinois Urbana-Champaign, “How to Kill Your Neighbor: A Story About Oxidative Stress”
February 2: Erin Carlson, University of Minnesota, “Chemical Microbiology: Translation and Control of Bacterial Behavior”
February 6: Rolf Müller, Helmholtz Institute for Pharmaceutical Research, Saarland, “Approaches Towards Innovative Anti-Infectives from Microbes”
February 7: Wei Mi, Yale University, “Regulation of Escherichia coli Lipopolysaccharide Synthesis”
February 21: Libin Xu, University of Washington, “Differential Contribution of Lipid Peroxidation Mechanisms to Ferroptosis”
February 28: Jeffrey Rathmell, Vanderbilt University Medical Center, “Immunometabolism and the Microenvironment in T Cell Function”
March 1: Pei Zhou, Duke University, “Novel Antibiotics Targeting Lipid A Biosynthesis in Gram-negative Bacteria”
March 6: Mia Huang, Scripps Research, La Jolla, “Taming Glycoconjugate Structure and Interactions in Development and Disease”
March 20: Andrei Osterman, Sanford Burnham Prebys, “Experimental Evolution and Genomics of Antibiotic Resistance”
March 27: Neil Pearson, GlaxoSmithKline, “Chemical Biology Platforms to Drug the Undruggable & Gepotidacin, a Novel Triazaacenaphthylene Bacterial Topoisomerase Inhibitor: Antibacterial Mechanism of Action”
April 3: Heidi Hamm, Vanderbilt University, “Protease Activated Receptor 4: Regulation of Platelet Function and Role in Inflammation”
April 10: Michelle Arkin, University of California-San Francisco, “Chemical Biology Approach to Caspase-6 as a New Target in Alzheimer’s Disease.” Co-sponsored by the Department of Pharmacology.
April 11: Steven Johnson, Indiana University Medical School, “Mechanistic Insights and Strategies to Target GroEL and HSP60 Chaperonin Systems for Therapeutic Development”
April 17: John Pascal, Université de Montréal, “Structures and Mechanisms of PARP Family Enzymes” Co-sponsored by the Center for Structural Biology
SPECIAL SEMINAR – August 21 (Add-to-Calendar): Berend Isermann, Institute of Laboratory Medicine at Leipzig University Hospital,”Tissue Factor and Interferon-Alpha Receptor-1 Interaction Constitutes a Thrombo-Inflammatory Switch”
September 4 (Add-to-Calendar): Patrick Griffin, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, “Structural Proteomics: Functional Dynamics of Nuclear Receptors”
September 11: Daniel Nelson, University of Maryland College of Agriculture & Natural Resources, “Beyond Antibiotics: Endolysins As Targeted Antibacterial Agents”
September 18: Emily Derbyshire, Duke University, “Interdisciplinary Approaches To Reveal Parasite Vulnerabilities”
September 25: Ronald Raines, Massachusetts Institute of Technology (MIT), “From Quantum Mechanics to the Clinic: Lessons from Collagen”
October 2: Wade Harper, Harvard Medical School, “Proteomic Exploration of Organelle Quality Control Mechanisms”
October 9: Jim Audia, FLARE Therapeutics, “Transcription Factor Drug Discovery: FX-909, a Potent, Selective PPARg Inverse Agonist for Muscle Invasive Urothelial Cancer”
October 30: Jane Aldrich, University of Florida, “Macrocyclic Tetrapeptides, Versatile Compounds for Potential Drug Development”
November 6: Sam Light, The University of Chicago, “Powering the Gut: How Microbial Bioenergetics Shape Bioactive Metabolite Production”
November 13: Tao Che, Washington University in St. Louis, “Structural Basis of Opioid Receptor Activation by Dissociative Hallucinogens”
November 20: Diana Mitrea, Dewpoint Therapeutics, “Leveraging Biomolecular Condensates to Discover the Next Generation Therapies”
December 4: Wilfred van der Donk, University of Illinois Urbana-Champaign, “Genome Mining for New Natural Products and New Chemistry”