Lorena Infante Lara
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Vanderbilt scientists pioneer an AI-driven drug discovery tool targeting RNAs
Vanderbilt researchers developed a deep-learning tool, RNAmigos2, that accelerates the discovery of RNA-targeting small-molecule drugs by 10,000 times compared to traditional methods, unlocking a promising new frontier in medicine. Read MoreApr. 24, 2025
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To cause cancer or not to cause cancer: What leads to H. pylori-induced stomach malignancies
Researchers from the Vanderbilt University Medical Center and Vanderbilt University have figured out how two bacterial elements present in only some Helicobacter pylori strains lead to molecular changes in host tissues that favor the development of gastric cancer. Read MoreApr. 2, 2025
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Vanderbilt researchers identify potential drug combinations to improve breast cancer treatment
Triple-negative breast cancer accounts for 10 percent of breast cancer cases in the U.S. annually. As T-cells that normally kill cancer cells often become exhausted and stop, Vanderbilt pharmacologists are seeking chemotherapy or targeted therapy approaches that can enhance the T-cell killing of cancer cells. Read MoreMar. 10, 2025
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Vanderbilt biomedical research paves the way for ‘hypoallergen’ treatments against peanut allergies
Peanuts cause the highest number of food allergy–related deaths in the U.S. Basic scientists at Vanderbilt uncover how the allergy works and suggest new potential treatments. Read MoreFeb. 24, 2025
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Vanderbilt and Northwestern labs discover new mechanisms that cause irregular heartbeat
Vanderbilt and Northwestern University researchers characterized a group of KCNQ1 variants probe their role in a common heart disorder called LQTS. They found that there are five classes of mutations that act through independent mechanisms, suggesting that a more tailored/personalized treatment approach could be beneficial for LQTS patients. Read MoreFeb. 18, 2025
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How do you maintain a cellular structure without a membrane? Researchers find that synapses can use liquids to create functional separations
Researchers from the School of Medicine Basic Sciences found that, although synapses are not bound by a membrane, they are still able to maintain a nanostructure necessary for evoked neurotransmission with the help of a physicochemical phenomenon called liquid-liquid phase separation. Read MoreFeb. 6, 2025
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Developmental biologists discover how a critical protein shapes gallbladder formation
Researchers from the School of Medicine Basic Sciences have discovered that the concentration of a critical protein influences the formation of the gallbladder and the bile duct system. Read MoreJan. 30, 2025
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Warren Center for Neuroscience Drug Discovery researchers create new compound to potentially treat negative and positive symptoms of schizophrenia
Researchers from the Warren Center for Neuroscience Drug Discovery, in collaboration with Boehringer Ingelheim, developed a compound that can treat both negative and positive symptoms of schizophrenia in rodents. The compound holds promise as an investigational tool and an inspiration for novel schizophrenia therapies. Read MoreJan. 16, 2025
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Fall 2024 Class Notes
Our School of Medicine Basic Sciences alums go far and wide. Check out the latest accomplishments from some of our alums! Read MoreDec. 11, 2024
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Research Snapshot: Spectroscopy and AI method provide unique window into protein structure and mechanism of action
Alexandra C. Schwartz, a recent Ph.D. graduate from the Chemical and Physical Biology Program, and colleagues developed an experimental and artificial intelligence–coupled methodology to explore the structural dynamics of membrane proteins. Read MoreDec. 2, 2024