Insulin
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Diabetes discoveries: Transforming understanding and care
Prior to insulin’s introduction to the clinic in 1922, life expectancy after a type 1 diabetes diagnosis was only one to two years. Even after insulin, without the understanding and technology we have today, managing diabetes was a struggle. Read MoreMar. 7, 2024
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CRISPR screen identifies role for a specific protein in insulin secretion
By Leah Mann Wenbiao Chen, Ph.D. The labs of Wenbiao Chen, associate professor of molecular physiology and biophysics, and Irina Kaverina, professor of cell and development biology, recently published a study in Molecular Metabolism focused on detecting genes that regulate insulin secretion. The authors demonstrated a new… Read MoreJan. 25, 2023
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Improving insulin sensitivity
By Wendy Bindeman Ambra Pozzi Ambra Pozzi, professor of medicine and of molecular physiology and biophysics, first author Kakali Ghoshal (a postdoc in the Pozzi lab), and colleagues recently published a study showing that supplementation with an analog of a lipid metabolite called epoxyeicosatrienoic acid, which is involved in insulin… Read MoreMar. 15, 2022