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Casein kinase II Regulation of the Hot1 Transcription Factor Promotes Stochastic Gene Expression Laura T. Burns and Susan R. Wente   Capsule Background: Dynamic signaling events are required for cell-to-cell gene expression differences during responses to environmental stress. Results: During hyperosmotic stress, casein kinase… Read More

Kinetochore-microtubule stability governs the metaphase requirement for Eg5 A. Sophia Gayek1 and Ryoma Ohi1, Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232 Kerry Bloom, Monitoring Editor Submitted March 3, 2014, Revised April 28, 2014, Accepted May 1, 2014. Abstract  … Read More

Mol Biol Cell. 2014 Mar;25(6):800-10. doi: 10.1091/mbc.E13-07-0374. Epub 2014 Jan29. Microtubule segment stabilization by RASSF1A is required for proper microtubule dynamics and Golgi integrity. Arnette C(1), Efimova N, Zhu X, Clark GJ, Kaverina I. Author information: (1)Department of Cell and Developmental Biology, Vanderbilt University Medical… Read More

Intestinal Brush Border Assembly Driven by Protocadherin-Based Intermicrovillar Adhesion Cell – Volume 157, Issue 2, 10 April 2014, Pages 433–446 Scott W. Crawley, David A. Shifrin Jr., Nathan E. Grega-Larson, Russell E. McConnell, Andrew E. Benesh, Suli Mao, Yuxi Zheng, Qing Yin Zheng, Ki Taek Nam, Bryan… Read More

TRIP/NOPO E3 ubiquitin ligase promotes ubiquitylation of DNA polymerase η Heather A. Wallace1,2,‡, Julie A. Merkle1,*,‡, Michael C. Yu1, Taloa G. Berg1, Ethan Lee1, Giovanni Bosco2 and Laura A. Lee1,§ Abstract We previously identified a Drosophila maternal effect-lethal mutant named ‘no poles’ (nopo). Embryos from nopo females undergo… Read More

Thomas Clandinin, Ph.D. Associate Professor, Department of Neurobiology, Stanford University School of Medicine MONDAY, MARCH 10, 2014 – 12:15 pm – 1220 MRB III… Read More

CDB Monday Seminar Series "The Role of Resident Mesenchymal Stem Cells in Pulmonary Disease" Susan Majka, Ph.D. – Associate Professor of Medicine  – CDB Secondary Faculty Candidate Monday, March 3, 2014 – 12:14 pm – 1220 MRB III… Read More

Robert J. Wechsler-Reya, Ph.D. Professor and Director, Tumor Development Program, Sanford-Burnham Medical Research Institute "Targeting the Stem Cells that Give Rise to Brain Tumors"                                                                                   Monday, February 24, 2014 12:15pm 1220 MRB III   Host: CDB Graduate Student Association… Read More

Motor and Tail Homology 1 (TH1) Domains Antagonistically Control Myosin-1 Dynamics Jessica N. Mazerik, Lewis J. Kraft, Anne K. Kenworthy, Matthew J. Tyska Abstract Class 1 myosins are monomeric motor proteins that fulfill diverse functions at the membrane/cytoskeletal interface. All myosins-1 contain a motor domain, which binds… Read More