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Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells. Read More

Irina Kaverina and others, recognized with Chancellor’s Awards for Research, which recognizes excellence in research, scholarship or creative expression. Chancellor's Awards Page VUcast faculty assembly… Read More

Identifying a borealin component of the yeast chromosome passenger complex. Read More

Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus. Huang X, Ketova T, Fleming JT, Wang H, Dey SK, Litingtung Y, Chiang C. Development. 2009 Aug;136(15):2535-43. Epub 2009 Jul 1. Note that VUMC reporter will do an aliquot report on this paper on… Read More

A surprising new function for intestinal cells in shaping theirlocal environment.Every cell lining the small intestine bristles with thousandsof tightly packed microvilli that project into the gut lumen,forming a brush border that absorbs nutrients and protects thebody from intestinal bacteria. McConnell et al. now find thatmicrovilli extend their… Read More

nature chemical biology 5, 195 – 196 (2009) doi:10.1038/nchembio0409-195 Yu-Ping Yang1 & Chris Wright1 Yu-Ping Yang and Chris Wright are in the Department of Cell and Developmental Biology and the Vanderbilt University Program in Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA. e-mail: chris.wright@vanderbilt.edu Abstract Small-molecule library… Read More

Vanderbilt Reporter, Lords of the contractile ring Cell division requires the formation of a contractile ring. While many protein components of this ring are known, how they interact with each other and with the plasma membrane remains unclear. Rachel Roberts-Galbraith, Kathy Gould, Ph.D., and colleagues are studying these… Read More

ER membrane–bending proteins are necessary for de novo nuclear pore formation T. Renee Dawson1, Michelle D. Lazarus1, Martin W. Hetzer2, and Susan R. Wente1 1 Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232 2 Molecular and Cell Biology Laboratory, Salk Institute… Read More

Cells cycle with no poles- no poles encodes a predicted E3 ubiquitin ligase required for early embryonic development of Drosophila Julie A. Merkle1, Jamie L. Rickmyre1, Aprajita Garg2, Erin B. Loggins1, Jeanne N. Jodoin1, Ethan Lee1, Louisa P. Wu2 and Laura A. Lee1,* 1 Department of Cell and… Read More

Diet and insulin in a stem cell niche Hormonal signaling in the fruit fly ovary keeps the niche young. Insulin reverses the effects of aging and poor diet, at least on cells within the ovaries of fruit flies. Biologists Daniela Drummond-Barbosa and Hwei-Jan Hsu of Vanderbilt University in… Read More