Author
Congratulations to David Jacobson! Another R01…..
Mar. 23, 2018—The new grant (1R01DK115620-01), titled DESIGNING SELECTIVE TALK-1 INHIBITORS TO REDUCE BETA-CELL DYSFUNCTION IN DIABETES, will test the central hypothesis that the inhibition of TALK-1 potassium channels in pancreatic beta cells normalizes Ca2+ homeostasis under diabetic conditions, preventing beta-cell dysfunction and maintaining euglycemia.
Work from the Cherrington/Moore labs published in Diabetes……
Mar. 16, 2018—Work from the Cherrington/Moore labs published in Diabetes……
Molecular metabolism publishes a paper by Nick Vierra
Mar. 14, 2018—Molecular metabolism publishes a paper by Nick Vierra….. TALK-1 reduces delta-cell endoplasmic reticulum and cytoplasmic calcium levels limiting somatostatin secretion
Diabetes publishes work from Jason Spaeth……
Mar. 14, 2018—Diabetes publishes work from Jason Spaeth…… Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning
Science Signaling paper from Nick Vierra (Jacobson lab)….
Mar. 14, 2018—Science Signaling paper from Nick Vierra (Jacobsen lab)…. TALK-1 channels control β cell endoplasmic reticulum Ca2+ homeostasis
Paper in Biological Psychiatry by Brian Shonesy…..
Mar. 14, 2018—Paper in Biological Psychiatry by Brian Shonesy….. Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior