My research project is focused on advancing our understanding of the molecular and kinetic mechanisms of energy maintenance by elucidating if and when MC4R induced Kir7.1 signaling is required for regulation of food intake and energy expenditure. We believe MC4R functions as a rheostat of energy maintenance by utilizing both tissue specific Gαs and Kir7.1 signaling modalities as well as unique kinetic aspects of these modalities. I am using an in vivo modeling system to test this hypothesis.
Graduate Student, Cone laboratory, Molecular Physiology & Biophysics
8435 MRB IV
(615) 936-8144 (lab)