Establishing Sickle Cell Disease Stroke Prevention Teams in Africa is Feasible: Program Evaluation Using the RE-AIM Framework

AUTHORS

Ghafuri DL , Abdullahi SU , Dambatta AH , Galadanci J , Tabari MA , Bello-Manga H , Idris N , Inuwa H , Tijjani A , Suleiman AA , Jibir BW , Gambo S , Gambo AI , Khalifa Y , Haliru L , Abdulrasheed S , Zakari MA , Greene BC , Trevathan E , Jordan LC , Aliyu MH , Baumann AA , DeBaun MR , . Journal of pediatric hematology/oncology. 2021 5 18; ().

PMID: 34001783 [PubMed].

ABSTRACT

We used the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework to evaluate a Stroke Prevention Team’s readiness to prevent strokes in children with sickle cell anemia living in northern Nigeria. The NIH sponsored Stroke Prevention Trial in Nigeria included a goal of a sustainable stroke prevention program. The program’s 1-year reach for transcranial Doppler screening was 14.7% (4710/32,000) of which 6.0% (281/4710) had abnormal velocities (≥200 cm/s). All participants with abnormal transcranial Doppler velocities were started on hydroxyurea (effectiveness). The leaders of all 5 hospitals agreed to adopt the program. After 1 year, program-implementation and maintenance rates were 100%, demonstrating the program’s feasibility and short-term sustainability.

Tags: alumni publications 2021