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Master of Public Health

Validity of diagnostic codes to identify cases of severe acute liver injury in the US Food and Drug Administration's Mini-Sentinel Distributed Database.

AUTHORS

Lo Re V , Haynes K , Goldberg D , Forde KA , Carbonari DM , Leidl KB , Hennessy S , Reddy KR , Pawloski PA , Daniel GW , Cheetham TC , Iyer A , Coughlin KO , Toh S , Boudreau DM , Selvam N , Cooper WO , Selvan MS , VanWormer JJ , Avigan MI , Houstoun M , Zornberg GL , Racoosin JA , Shoaibi A , . Pharmacoepidemiology and drug safety. 2013 8 1; 22(8). 861-72

ABSTRACT

The validity of International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes to identify diagnoses of severe acute liver injury (SALI) is not well known. We examined the positive predictive values (PPVs) of hospital ICD-9-CM diagnoses in identifying SALI among health plan members in the Mini-Sentinel Distributed Database (MSDD) for patients without liver/biliary disease and for those with chronic liver disease (CLD).

The validity of International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes to identify diagnoses of severe acute liver injury (SALI) is not well known. We examined the positive predictive values (PPVs) of hospital ICD-9-CM diagnoses in identifying SALI among health plan members in the Mini-Sentinel Distributed Database (MSDD) for patients without liver/biliary disease and for those with chronic liver disease (CLD).

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