Primary stroke prevention in Nigerian children with sickle cell disease (SPIN): Challenges of conducting a feasibility trial.
AUTHORS
Galadanci
NA ,
Abdullahi
SU ,
Tabari
MA ,
Abubakar
S ,
Belonwu
R ,
Salihu
A ,
Neville
K ,
Kirkham
F ,
Inusa
B ,
Shyr
Y ,
Phillips
S ,
Kassim
AA ,
Jordan
LC ,
Aliyu
MH ,
Covert
BV ,
DeBaun
MR ,
. Pediatric blood & cancer. 2014 11 14; ().
- PMID: 25399822 [PubMed].
ABSTRACT
The majority of children with sickle cell disease (SCD), approximately 75%, are born in sub-Saharan Africa. For children with elevated transcranial Doppler (TCD) velocity, regular blood transfusion therapy for primary stroke prevention is standard care in high income countries, but is not feasible in sub-Saharan Africa.
The majority of children with sickle cell disease (SCD), approximately 75%, are born in sub-Saharan Africa. For children with elevated transcranial Doppler (TCD) velocity, regular blood transfusion therapy for primary stroke prevention is standard care in high income countries, but is not feasible in sub-Saharan Africa.
Tags: Alumni Publications 2014