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Antibodies, boosters and optimizing SARS-CoV-2 vaccine for transplantation: A call for more research


AUTHORS

Ison MG , Blumberg E , Halasa N , Kaul D , Theodoropoulos NM , Wolfe CR , . American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2021 7 9; ().

ABSTRACT

Despite emerging data suggesting reduced antibody responses among SOT recipients following SARS-CoV-2 vaccine, critical unanswered questions remain. The clinical implications of the reduced humoral response need to be assessed through prospective studies. Studies are likewise needed to inform which vaccine dosing strategies result in improved immunity and if such approaches maximize protection against severe infection in the vulnerable transplant population.



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