Balanced crystalloids versus saline in the intensive care unit: study protocol for a cluster-randomized, multiple-crossover trial.
AUTHORS
Semler
MW ,
Self
WH ,
Wang
L ,
Byrne
DW ,
Wanderer
JP ,
Ehrenfeld
JM ,
Stollings
JL ,
Kumar
AB ,
Hernandez
A ,
Guillamondegui
OD ,
May
AK ,
Siew
ED ,
Shaw
AD ,
Bernard
GR ,
Rice
TW ,
,
,
. Trials. 2017 3 16; 18(1). 129
- PMID: 28302179 [PubMed].
ABSTRACT
Saline, the intravenous fluid most commonly administered to critically ill adults, contains a high chloride content, which may be associated with acute kidney injury and death. Whether using balanced crystalloids rather than saline decreases the risk of acute kidney injury and death among critically ill adults remains unknown.
Saline, the intravenous fluid most commonly administered to critically ill adults, contains a high chloride content, which may be associated with acute kidney injury and death. Whether using balanced crystalloids rather than saline decreases the risk of acute kidney injury and death among critically ill adults remains unknown.
Tags: Alumni Publications 2017