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Master of Public Health

Comparative Treatment Outcomes for Idiopathic Subglottic Stenosis: 5-Year Update

AUTHORS

Tierney WS , Huang LC , Chen SC , Berry LD , Anderson C , Amin MR , Benninger MS , Blumin JH , Bock JM , Bryson PC , Castellanos PF , Clary MS , Cohen SM , Crawley BK , Dailey SH , Daniero JJ , de Alarcon A , Donovan DT , Edell ES , Ekbom DC , Fink DS , Franco RA , Garrett CG , Guardiani EA , Hillel AT , Hoffman HT , Hogikyan ND , Howell RJ , Johns MM , Kasperbauer JL , Khosla SM , Kinnard C , Kupfer RA , Langerman AJ , Lentz RJ , Lorenz RR , Lott DG , Makani SS , Maldonado F , Matrka L , McWhorter AJ , Merati AL , Mori M , Netterville JL , O'Dell K , Ongkasuwan J , Postma GN , Reder LS , Rohde SL , Richardson BE , Rickman OB , Rosen CA , Rohlfing M , Rutter MJ , Sandhu GS , Schindler JS , Schneider GT , Shah RN , Sikora AG , Sinard RJ , Smith ME , Smith LJ , Soliman AMS , Sveinsdóttir S , Veivers D , Verma SP , Weinberger PM , Weissbrod PA , Wootten CT , Shyr Y , Francis DO , Gelbard A , . Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2023 1 19; ().

ABSTRACT

The North American Airway Collaborative (NoAAC) previously published a 3-year multi-institutional prospective cohort study showing variation in treatment effectiveness between 3 primary surgical techniques for idiopathic subglottic stenosis (iSGS). In this report, we update these findings to include 5 years of data evaluating treatment effectiveness. Patients in the NoAAC cohort were re-enrolled for 2 additional years and followed using the prespecified published protocol. Consistent with prior data, prospective observation of 487 iSGS patients for 5 years showed treatment effectiveness differed by modality. Cricotracheal resection maintained the lowest rate of recurrent operation (5%), followed by endoscopic resection with adjuvant medical therapy (30%) and endoscopic dilation (50%). These data support the initial observations and continue to provide value to providers and patients navigating longitudinal decision-making. Level of evidence: 2-prospective cohort study.

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