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Contribution of serology assays in the evaluation of influenza virus infection rates and vaccine efficacy in pregnant women: Report from randomized controlled trials.


AUTHORS

Madhi SA , Nunes M , Weinberg A , Kuwanda L , Hugo A , Jones S , van Niekerk N , Ortiz JR , Neuzil KM , Klugman KP , Simoes EA , Cutland CL , , . Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2017 3 21; ().

ABSTRACT

The utility of serological testing to evaluate vaccine efficacy of seasonal inactivated influenza vaccine (IIV) is controversial. We aimed to evaluate the efficacy of IIV against serologically-diagnosed influenza infection (SDI), and reverse-transcription polymerase chain reaction confirmed influenza illness (PCR-CI) in women vaccinated during pregnancy.


The utility of serological testing to evaluate vaccine efficacy of seasonal inactivated influenza vaccine (IIV) is controversial. We aimed to evaluate the efficacy of IIV against serologically-diagnosed influenza infection (SDI), and reverse-transcription polymerase chain reaction confirmed influenza illness (PCR-CI) in women vaccinated during pregnancy.


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